CAJ | 학술논문

目的探讨兔挤压伤后不同时间点的心肌应变率,评估挤压伤后心脏继发损伤.方法新西兰家兔42只,雌雄不拘,应用自制挤压器具按标准制作挤压伤模型,42只家兔随机分为对照组、解压即刻、解压后6、12、24、48、72 h共7组,每组6只,每只家兔均连续检测挤压前及解压后不同时间点左室心肌应变和应变率等情况.结果左室心肌感兴趣区域的应变和应变率在解压后12h至24 h降至最低(P＜0.01);72 h后逐渐恢复并相对稳定在一定水平,但与对照组比较,左室心肌应变和应变率仍降低(P＜0.05).结论挤压伤伤后12～24 h是心肌受损的达峰时间段,超声应变率成像能较精准、客观地评价心肌收缩性能.
목적 탐토토제압상후불동시간점적심기응변솔,평고제압상후심장계발손상.방법 신서란가토42지,자웅불구,응용자제제압기구안표준제작제압상모형,42지가토수궤분위대조조、해압즉각、해압후6、12、24、48、72 h공7조,매조6지,매지가토균련속검측제압전급해압후불동시간점좌실심기응변화응변솔등정황.결과 좌실심기감흥취구역적응변화응변솔재해압후12h지24 h강지최저(P＜0.01);72 h후축점회복병상대은정재일정수평,단여대조조비교,좌실심기응변화응변솔잉강저(P＜0.05).결론 제압상상후12～24 h시심기수손적체봉시간단,초성응변솔성상능교정준、객관지평개심기수축성능.
Objective To study the rabbits' cardiac secondary damaged after crush injury at different time point by strain rate imaging.Methods Forty-two New Zealand rabbbits,female and male not confined,were random divided into seven groups including control group,and other six groups,including loosed pressure immediately,and at 6,12,24,48,and 72 hours after crush injury,and the left ventricular myocardial efficiency were detected by strain rate imaging consecutively at different time point.Results The left ventricular myocardial strain and strain rate of the region of interestwere decreased lowest after loosed pressure 12 to 24 h(P ＜0.01),and which were rised gradually after 72 h.Conclusions The rabbits' left ventriclular myocardial efficiency are obvious decreased after crush injury,and after loosed pressure 12 to 24 h are peak time.The left ventricular myocardial efficiency can be evaluated precisely and objectively by strain rate imaging.