CAJ | 학술논문

目的探讨声触诊组织成像技术(VTI)在甲状腺实性小结节鉴别诊断中的应用价值.方法对35例甲状腺患者41个小结节进行常规超声及VTI检查,通过VTI图像对小结节硬度进行评分,并计算小结节VTI图像与灰阶图像面积比.以病理诊断为金标准,绘制ROC曲线,找出面积比预测甲状腺恶性结节的最佳截点.结果 41个甲状腺小结节病理证实良性23个,恶性18个.甲状腺恶性结节VTI评分4分及以上的出现率明显高于良性组(88.9％对8.7％,P＜0.01).甲状腺恶性结节VTI图像与灰阶图像面积比高于良性结节(1.67±0.16对1.23±0.12,P＜0.01).以面积比1.46为截点诊断甲状腺恶性结节的敏感性88.9％,特异性95.7％.结论 VTI技术可提供甲状腺结节硬度方面的信息,在甲状腺实性小结节鉴别诊断中具有较高的应用价值.
목적 탐토성촉진조직성상기술(VTI)재갑상선실성소결절감별진단중적응용개치.방법 대35례갑상선환자41개소결절진행상규초성급VTI검사,통과VTI도상대소결절경도진행평분,병계산소결절VTI도상여회계도상면적비.이병리진단위금표준,회제ROC곡선,조출면적비예측갑상선악성결절적최가절점.결과 41개갑상선소결절병리증실량성23개,악성18개.갑상선악성결절VTI평분4분급이상적출현솔명현고우량성조(88.9％대8.7％,P＜0.01).갑상선악성결절VTI도상여회계도상면적비고우량성결절(1.67±0.16대1.23±0.12,P＜0.01).이면적비1.46위절점진단갑상선악성결절적민감성88.9％,특이성95.7％.결론 VTI기술가제공갑상선결절경도방면적신식,재갑상선실성소결절감별진단중구유교고적응용개치.
Objective To investigate the value of virtual touch tissue imaging (VTI) in the differential diagnosis of small solid thyroid nodules.Methods 35 patients with 41 small thyroid nodules were examined by conventional ultrasound and VTI examination.The stiffness of the nodules in VTI images was scored.Area ratios of VTI and gray scale images of nodules were calculated.The pathological diagnosis was used as the gold standard.The ROC curve was drawn to determine the cut off point of area ratio to predict thyroid cancer.Results 41 small thyroid nodules were confirmed by pathological diagnosis,including 23 benign and 18 malignant nodules.Compared with benign nodules,the ratio of VTI hardness score ≥4 was significantly higher in the malignant nodules (88.9％ vs 8.7％,P ＜0.01).Compared with benign nodules,the area ratios of malignant nodules were higher (1.67 ± 0.16 vs 1.23 ± 0.12,P ＜0.01).When 1.46 was set as the cut off point of areas ratio,the sensitivity and specificity of diagnosing thyroid cancer were 88.9％ and 95.7％,respectively.Conclusions VTI can provide information about thyroid nodules hardness.It has high value in the differential diagnosis of small solid thyroid nodules.