CAJ | 학술논문

目的采用剪切波实时组织弹性成像技术测定乳腺病灶整体弹性模量值及离散度(Std),评价其在乳腺病灶良恶性诊断中的价值.方法对123例女性患者共计134个乳腺病灶及74例正常乳腺腺体组织进行实时弹性成像,测定组织整体弹性模量值和Std值,应用ROC曲线分别计算两种数据的诊断界值.结果以组织病理为诊断金标准,良、恶性病灶与正常腺体的整体弹性模量值和Std值差异均具有统计学意义；ROC曲线分析,约登指数最大时,病灶整体弹性模量诊断界值取41.01 kPa,灵敏性68.5％,特异性83.8％；病灶Std值诊断界值取12.25 kPa,灵敏性87.0％,特异性88.7％.结论乳腺病灶整体弹性模量值和Std值均可定量反映病灶弹性特征,有助于临床鉴别诊断乳腺病灶的良恶性.
목적 채용전절파실시조직탄성성상기술측정유선병조정체탄성모량치급리산도(Std),평개기재유선병조량악성진단중적개치.방법 대123례녀성환자공계134개유선병조급74례정상유선선체조직진행실시탄성성상,측정조직정체탄성모량치화Std치,응용ROC곡선분별계산량충수거적진단계치.결과 이조직병리위진단금표준,량、악성병조여정상선체적정체탄성모량치화Std치차이균구유통계학의의；ROC곡선분석,약등지수최대시,병조정체탄성모량진단계치취41.01 kPa,령민성68.5％,특이성83.8％；병조Std치진단계치취12.25 kPa,령민성87.0％,특이성88.7％.결론 유선병조정체탄성모량치화Std치균가정량반영병조탄성특정,유조우림상감별진단유선병조적량악성.
Objective To evaluate the value of supersonic shear wave elastrography(SWE) in the diagnosis of benign and malignant breast lesions.Methods SWE was performed on 134 breast lesions of 123 female patients and 74 normal breast glands to determine the values of overall elastic modulus and dispersion,and ROC curves were used to assess the diagnosis boundary value of two kinds of data respectively.Results According to the diagnostic gold standard-histopathology,the values of overall elastic modulus and dispersion were statistically significant when comparing benign lesions and malignant lesions with normal glands.ROC curve displayed that,when the Youden index reached to maximum,the diagnosis boundary value of overall elastic modulus was 41.01 kPa,the sensitivity and specificity of the value were 68.5％ and 83.8％ respectively; the diagnosis boundary value of dispersion was 12.25 kPa,the sensitivity and specificity of the value were 87.0％ and 88.7％ respectively.Conclusions The values of overall elastic modulus and dispersion for solid breast lesions can be used to reflect the elastic characteristics of lesions quantificationally,which is useful to diagnose benign and malignant breast lesions in clinical.