CAJ | 학술논문

目的应用实时三维超声斑点追踪成像(real-time-dimension speckle tracking imaging,RT3D-STI)技术评价冠心病患者的左室整体收缩功能,探讨RT3D-STI各项应变指标诊断冠心病的临床应用价值.方法收集经冠脉造影证实的冠心病患者55例,对照组34例.应用RT3D-STI采集心尖全容积图像得出两组左室整体长轴应变(GLS)、左室整体轴向应变(GCS)、左室整体径向应变(GRS)、左室整体面积应变(GAS)及左室射血分数(LVEF)等,分析应变值对冠心病的诊断价值.结果冠心病组GLS、GCS、GRS及GAS均较对照组减低,差异有统计学意义(P＜0.05).ROC曲线显示GLS诊断冠心病的曲线下面积(AUC)最大,约91.6％,当GLS截断值为-12.5时,GLS的敏感性最高约90.3％,Youden指数0.612;当GAS截断值为-23.0时,GAS特异性最高约95.8％,Youden指数0.539.相关分析表明冠心病组GLS、GAS与LVEF显著相关(r分别为-0.860,-0.926).结论应用RT3D-STI诊断冠心病的各项指标中,GLS敏感度最高,GAS特异度最高.RT3D-STI可早期发现冠心病患者左室整体收缩功能的变化.
목적 응용실시삼유초성반점추종성상(real-time-dimension speckle tracking imaging,RT3D-STI)기술평개관심병환자적좌실정체수축공능,탐토RT3D-STI각항응변지표진단관심병적림상응용개치.방법 수집경관맥조영증실적관심병환자55례,대조조34례.응용RT3D-STI채집심첨전용적도상득출량조좌실정체장축응변(GLS)、좌실정체축향응변(GCS)、좌실정체경향응변(GRS)、좌실정체면적응변(GAS)급좌실사혈분수(LVEF)등,분석응변치대관심병적진단개치.결과 관심병조GLS、GCS、GRS급GAS균교대조조감저,차이유통계학의의(P＜0.05).ROC곡선현시GLS진단관심병적곡선하면적(AUC)최대,약91.6％,당GLS절단치위-12.5시,GLS적민감성최고약90.3％,Youden지수0.612;당GAS절단치위-23.0시,GAS특이성최고약95.8％,Youden지수0.539.상관분석표명관심병조GLS、GAS여LVEF현저상관(r분별위-0.860,-0.926).결론 응용RT3D-STI진단관심병적각항지표중,GLS민감도최고,GAS특이도최고.RT3D-STI가조기발현관심병환자좌실정체수축공능적변화.
Objective To evaluate left ventricular systolic function by real-time three-dimension speckle tracking imaging (RT3D-STI) in coronary artery diseases (CHD) patients,to determine the clinical value of RT3D-STI in CHD.Methods 34 control subjects and 55 patients with CHD by coronary angiography were involved.Left ventricular global longitudinal strain (GLS),left ventricular global circumferential strain (GCS),left ventricular global radial strain (GRS),left ventricular global area strain (GAS) and left ventricular ejection fraction (LVEF),etc,was acquired by RT3D-STI,respectively.The parameters by RT3D-STI to diagnose CHD were analyzed.Results Compared with control group,GLS,GCS,GRS and GAS were significantly decreased in CHD group (P ＜ 0.05).The area under receiver operating characteristics (AUC) curve of GLS to diagnose CHD was 91.6％.The cutoff value,the sensitivity and Youden index of GLS were-12.5,90.3 ％ and 0.612,respectiuely.The cutoff value,the sensitivity and Youden index of GAS were-23.0,95.8％ and 0.539,respectiuely.GLS,GAS correlated well with LVEF in CHD group (r =-0.860,r =-0.926).Conclusions GLS is the most sensitivity and GAS is the most specificity in the all of strain parameters.RT3D-STI can early show the changes of left ventricular global systolic function in patients with CHD.