CAJ | 학술논문

目的应用单心动周期实时三维超声心动图评价房间隔缺损(ASD)右心室形态及功能.方法选取34例健康志愿者(对照组)和27例接受介入治疗的房间隔缺损患者(ASD组),对所有研究对象进行单心动周期实时三维超声心动图检查,分别测量右室舒张末容积(IEDVRV)、右室收缩末容积(IESVRV)、右室每搏量(ISVRV)、右室射血分数(RVEF),同时对ASD患者通过三尖瓣反流估测肺动脉收缩压(PASP)与心导管测得平均肺动脉收缩压(PAMP),两者分别与三维右心室舒张及收缩末容积进行相关性研究.结果 ASD组三维右心室舒张末容积(IEDVRv)、三维右心室收缩末容积(IESVRv)、三维右心室每搏输出量(ISVRV)及三维右室射血分数(RVEF)均大于对照组(P＜0.05),ASD组单心动周期三维右室容积随时间变化幅度较对照组低,两组均在心动周期40％处出现最大变化值,且三维右心室形态相关参数(IEDVRV、IESVRv)与右心导管所测平均肺动脉压力(PAMP)及通过三尖瓣反流测得肺动脉收缩压(PASP)呈正相关.结论单心动周期实时三维超声能够更准确、快速地反映ASD患者右心室形态及功能的改变,通过右室容积的变化可以无创地间接判断出肺动脉压力的高低.
목적 응용단심동주기실시삼유초성심동도평개방간격결손(ASD)우심실형태급공능.방법 선취34례건강지원자(대조조)화27례접수개입치료적방간격결손환자(ASD조),대소유연구대상진행단심동주기실시삼유초성심동도검사,분별측량우실서장말용적(IEDVRV)、우실수축말용적(IESVRV)、우실매박량(ISVRV)、우실사혈분수(RVEF),동시대ASD환자통과삼첨판반류고측폐동맥수축압(PASP)여심도관측득평균폐동맥수축압(PAMP),량자분별여삼유우심실서장급수축말용적진행상관성연구.결과 ASD조삼유우심실서장말용적(IEDVRv)、삼유우심실수축말용적(IESVRv)、삼유우심실매박수출량(ISVRV)급삼유우실사혈분수(RVEF)균대우대조조(P＜0.05),ASD조단심동주기삼유우실용적수시간변화폭도교대조조저,량조균재심동주기40％처출현최대변화치,차삼유우심실형태상관삼수(IEDVRV、IESVRv)여우심도관소측평균폐동맥압력(PAMP)급통과삼첨판반류측득폐동맥수축압(PASP)정정상관.결론 단심동주기실시삼유초성능구경준학、쾌속지반영ASD환자우심실형태급공능적개변,통과우실용적적변화가이무창지간접판단출폐동맥압력적고저.
Objective To investigate the right ventricular morphology and function of patients with atrial septal defects by single beat real-time three-dimensional echocardiography.Methods Thirty-four healthy volunteers and twenty-seven ASD patients were enrolled consecutively as normal controls and the ASD group respectively.Single cardiac cycle real-time three dimensional echocardiography was performed in all to evaluate parameters concerning modality and systolic function of participants' right ventricle.The relationship of indexed right ventricular end diastolic volume (IEDVRV) and end systolic volume(IESVRV)with mean pulmonary arterial pressure measured through cardiac catheter and systolic pulmonary artery pressure calculated though the three tricuspid regurgitation were observed.Results Indexed right ventricular end diastolic volume (IEDVRv),end systolic volume(IESVRV),right ventricular stroke volume (ISVRV) and right ventrieular ejection fraction (RVEF) were greater in the ASD group than in controls (P ＜ 0.05).IEDVRv and IESVRV had positive relation with pulmonary pressure measured by cardiac catheter and systolic pulmonary artery pressure calculated though the three tricuspid regurgitation.Conclusions Single cardiac cycle real-time three dimensional echocardiography has an obvious advantage than normal test in evaluating the change of the right ventricular function and shapes,furthermore,single cardiac cycle real-time three dimensional echocardiography can indirectly determined the pressure of the pulmonary without wound.