中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2013年
5期
422-425
,共4页
姜双全%姜丽丽%田家玮%王影%苏雁欣%冷晓萍%杜国庆
薑雙全%薑麗麗%田傢瑋%王影%囌雁訢%冷曉萍%杜國慶
강쌍전%강려려%전가위%왕영%소안흔%랭효평%두국경
超声检查%甲状腺结节%Logistic模型%弹性成像
超聲檢查%甲狀腺結節%Logistic模型%彈性成像
초성검사%갑상선결절%Logistic모형%탄성성상
Ultrasonography%Thyroid nodule%Logistic medels%Elastography
目的 运用Logistic回归筛选能够鉴别甲状腺微小结节良恶性的超声声像图特征,建立以声像图特征为自变量的二分类Logistic回归模型,评价常规超声及超声弹性成像在甲状腺微小结节良恶性鉴别诊断中的价值.方法 对140例患者共166枚甲状腺微小结节(最大径≤10 mm)的二维、彩色多普勒及超声弹性成像检查图片进行回顾性分析,以病理结果为金标准,建立回归模型.比较进入方程中的变量的优势比(OR),评价各变量尤其是弹性成像的鉴别诊断效能.结果 经过Logistic逐步回归分析,共筛选出4个具有统计学意义的特征变量,包括:边界、钙化、结节内部成分及弹性评分.其中弹性评分的OR值高于其他自变量.结论 二分类Logistic回归模型筛选出对甲状腺微小结节病理性质有鉴别诊断意义的特征变量,超声弹性成像较其他超声特征更有优势.联合应用超声弹性成像及二维声像图特征对于甲状腺微小结节的确诊具有重要临床意义.
目的 運用Logistic迴歸篩選能夠鑒彆甲狀腺微小結節良噁性的超聲聲像圖特徵,建立以聲像圖特徵為自變量的二分類Logistic迴歸模型,評價常規超聲及超聲彈性成像在甲狀腺微小結節良噁性鑒彆診斷中的價值.方法 對140例患者共166枚甲狀腺微小結節(最大徑≤10 mm)的二維、綵色多普勒及超聲彈性成像檢查圖片進行迴顧性分析,以病理結果為金標準,建立迴歸模型.比較進入方程中的變量的優勢比(OR),評價各變量尤其是彈性成像的鑒彆診斷效能.結果 經過Logistic逐步迴歸分析,共篩選齣4箇具有統計學意義的特徵變量,包括:邊界、鈣化、結節內部成分及彈性評分.其中彈性評分的OR值高于其他自變量.結論 二分類Logistic迴歸模型篩選齣對甲狀腺微小結節病理性質有鑒彆診斷意義的特徵變量,超聲彈性成像較其他超聲特徵更有優勢.聯閤應用超聲彈性成像及二維聲像圖特徵對于甲狀腺微小結節的確診具有重要臨床意義.
목적 운용Logistic회귀사선능구감별갑상선미소결절량악성적초성성상도특정,건립이성상도특정위자변량적이분류Logistic회귀모형,평개상규초성급초성탄성성상재갑상선미소결절량악성감별진단중적개치.방법 대140례환자공166매갑상선미소결절(최대경≤10 mm)적이유、채색다보륵급초성탄성성상검사도편진행회고성분석,이병리결과위금표준,건립회귀모형.비교진입방정중적변량적우세비(OR),평개각변량우기시탄성성상적감별진단효능.결과 경과Logistic축보회귀분석,공사선출4개구유통계학의의적특정변량,포괄:변계、개화、결절내부성분급탄성평분.기중탄성평분적OR치고우기타자변량.결론 이분류Logistic회귀모형사선출대갑상선미소결절병이성질유감별진단의의적특정변량,초성탄성성상교기타초성특정경유우세.연합응용초성탄성성상급이유성상도특정대우갑상선미소결절적학진구유중요림상의의.
Objective To select sonogram features for the differential diagnosis of benign and malignant thyroid small nodules by Logistics regression analysis,and to contribute the binary Logistic regression model of sonogram features as independent variable and evaluate the value of conventional ultrasonography and ultrasound elastography (UE) in the differential diagnosis of benign and malignant thyroid small nodules.Methods 166 thyroid nodules (≤ 10 mm) in 140 patients were reviewed and analyzed by 2D ultrasound,color Doppler flow imaging and UE.A Logistic model was obtained based on pathology as golden diagnosis criteria.The odds ratio of variables in the equation were compared to assess various variables,especially the efficacy of elastography in the diagnosis.Results Four statistically significant features were finally entering the Logistic stepwise regression model,including shape,calcification,the internal component of nodules and elasticity score.And the odds ratio of the elasticity score was higher than other features.Conclusions The analysis of binary Logistic regression can select the valuable variables for the diagnosis of pathological nature of thyroid small nodules.UE has much more dominances than other features.The combinated application of UE and 2D ultrasonic features plays a great clinical role in the final diagnosis of thyroid small nodules.