CAJ | 학술논문

目的探讨实时剪切波弹性成像(real-time shear wave elastography,SWE)技术检测肝硬度的可行性,建立成年人正常肝剪切波弹性模量参考值范围.方法应用SWE技术,对335例健康体检者进行肝弹性模量值检测,获得正常值范围,分析性别及年龄对肝弹性模量的影响,其中30例受检者经两位医生分别检测.结果 335例受检者中有329例成功,成功率为98.2％.正常肝弹性模量均值为(5.023±0.966)kPa,95％可信区间为4.918-5.128 kPa,不同年龄及性别组间测值比较差异无统计学意义(P =0.218、P=0.271),不同操作者对同一组受检者检测的肝弹性模量均值差异无统计学意义(P =0.498),组间相关系数ICC为0.925.结论 SWE技术评估正常成人肝硬度的重复性及稳定性好,成年人正常肝实时剪切波弹性模量均值为(5.023±0.966)kPa;性别及年龄对肝弹性模量值检测无影响.
목적 탐토실시전절파탄성성상(real-time shear wave elastography,SWE)기술검측간경도적가행성,건립성년인정상간전절파탄성모량삼고치범위.방법 응용SWE기술,대335례건강체검자진행간탄성모량치검측,획득정상치범위,분석성별급년령대간탄성모량적영향,기중30례수검자경량위의생분별검측.결과 335례수검자중유329례성공,성공솔위98.2％.정상간탄성모량균치위(5.023±0.966)kPa,95％가신구간위4.918-5.128 kPa,불동년령급성별조간측치비교차이무통계학의의(P =0.218、P=0.271),불동조작자대동일조수검자검측적간탄성모량균치차이무통계학의의(P =0.498),조간상관계수ICC위0.925.결론 SWE기술평고정상성인간경도적중복성급은정성호,성년인정상간실시전절파탄성모량균치위(5.023±0.966)kPa;성별급년령대간탄성모량치검측무영향.
Objective To explore the feasibility of detecting liver stiffness by real-time shear wave elastography (SWE) and establish a reference range of shear modulus in healthy liver of adults.Methods 335 adults underwent SWE detection to obtain the shear modulus of livers.The effects of different gender and age on the shear modulus in normal adult were analyzed.Thirty subjects were performed by two operators respectively to evaluate interobserver agreement.Results 329 health volunteers were detected successfully.The success rate was 98.2 ％.The mean value of SWE measurements in normal individuals was (5.023 ± 0.966)kPa.The liver shear modulus of healthy adults had a 95％ confidence interval from 4.918-5.128 kPa.There were no significant differences between the mean SWE values in men vs women (P =0.218),also among different age groups (P =0.271).No statistically significant was observed between the mean SWE values obtained by two different operators (P =0.498),interobserver ICC value was 0925.Conclusions SWE is a repeatability and stability method to access liver stiffness on healthy subjects.In our study the mean liver stiffness value obtained by SWE in healthy subjects was 5.023 kPa.The mean liver stiffness value obtained by SWE did not influenced by sex and age.