中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2013年
6期
518-521
,共4页
杨宇%张晶%韩治宇%周洪雨%马霞%徐瑞芳%于杰%于明安
楊宇%張晶%韓治宇%週洪雨%馬霞%徐瑞芳%于傑%于明安
양우%장정%한치우%주홍우%마하%서서방%우걸%우명안
超声检查%微波/治疗应用%子宫肿瘤%平滑肌瘤
超聲檢查%微波/治療應用%子宮腫瘤%平滑肌瘤
초성검사%미파/치료응용%자궁종류%평활기류
Ultrasonography%Microwaves/therapeuticuse%Uterine neoplasms%Leiomyoma
目的 评价超声引导经皮微波消融(UPMWA)治疗子宫黏膜下肌瘤的临床疗效.方法 对19例经UPMWA治疗的子宫黏膜下肌瘤患者进行临床疗效评价的前瞻性研究.在术后3、12个月患者来院复查时,记录肌瘤体积、血红蛋白量(Hb)、子宫肌瘤症状及与健康相关生活质量(UFS-QOL)评分以及副作用、并发症,并同治疗前相应指标相比较.结果 19例患者的19枚黏膜下肌瘤中,0型5枚、Ⅰ型6枚、Ⅱ型8枚.消融后8例患者有坏死组织排出,肌瘤体积、Hb及UFS-QOL的症状严重程度评分(SSS)和健康相关生活质量评分(HRQL)分别从治疗前的(78.75±65.71)cm3、(89.50±21.34)g/L、(36.34±17.65)分及(54.38±25.60)分变化至消融后12个月的(11.13±8.78)cm3(P=0.000)、(124.60±14.00) g/L(P=0.000)、(15.30±13.58)分(P=0.000)及(83.35±12.28)分(P=0.000).患者主要不良反应为阴道流液,在治疗后2～4周内多数患者症状可自行消失,未出现严重并发症.结论 UPMWA治疗子宫黏膜下肌瘤临床效果确切,成为其保守治疗可供选择的方法.
目的 評價超聲引導經皮微波消融(UPMWA)治療子宮黏膜下肌瘤的臨床療效.方法 對19例經UPMWA治療的子宮黏膜下肌瘤患者進行臨床療效評價的前瞻性研究.在術後3、12箇月患者來院複查時,記錄肌瘤體積、血紅蛋白量(Hb)、子宮肌瘤癥狀及與健康相關生活質量(UFS-QOL)評分以及副作用、併髮癥,併同治療前相應指標相比較.結果 19例患者的19枚黏膜下肌瘤中,0型5枚、Ⅰ型6枚、Ⅱ型8枚.消融後8例患者有壞死組織排齣,肌瘤體積、Hb及UFS-QOL的癥狀嚴重程度評分(SSS)和健康相關生活質量評分(HRQL)分彆從治療前的(78.75±65.71)cm3、(89.50±21.34)g/L、(36.34±17.65)分及(54.38±25.60)分變化至消融後12箇月的(11.13±8.78)cm3(P=0.000)、(124.60±14.00) g/L(P=0.000)、(15.30±13.58)分(P=0.000)及(83.35±12.28)分(P=0.000).患者主要不良反應為陰道流液,在治療後2～4週內多數患者癥狀可自行消失,未齣現嚴重併髮癥.結論 UPMWA治療子宮黏膜下肌瘤臨床效果確切,成為其保守治療可供選擇的方法.
목적 평개초성인도경피미파소융(UPMWA)치료자궁점막하기류적림상료효.방법 대19례경UPMWA치료적자궁점막하기류환자진행림상료효평개적전첨성연구.재술후3、12개월환자래원복사시,기록기류체적、혈홍단백량(Hb)、자궁기류증상급여건강상관생활질량(UFS-QOL)평분이급부작용、병발증,병동치료전상응지표상비교.결과 19례환자적19매점막하기류중,0형5매、Ⅰ형6매、Ⅱ형8매.소융후8례환자유배사조직배출,기류체적、Hb급UFS-QOL적증상엄중정도평분(SSS)화건강상관생활질량평분(HRQL)분별종치료전적(78.75±65.71)cm3、(89.50±21.34)g/L、(36.34±17.65)분급(54.38±25.60)분변화지소융후12개월적(11.13±8.78)cm3(P=0.000)、(124.60±14.00) g/L(P=0.000)、(15.30±13.58)분(P=0.000)급(83.35±12.28)분(P=0.000).환자주요불량반응위음도류액,재치료후2～4주내다수환자증상가자행소실,미출현엄중병발증.결론 UPMWA치료자궁점막하기류림상효과학절,성위기보수치료가공선택적방법.
Objective To evaluate the efficiency of ultrasound-guided percutaneous microwave ablation (UPMWA) in treating submucous uterine fibroids.Methods 19 patients with 19 submucous uterine fibroids were admitted from March 2009 to December 2012.Microwave antenna was inserted into the centre of fibroid percutaneously and work in a reasonable energy.After ablation,contrast-enhanced ultrasound (CEUS) and contrast enhanced magnatic resonance imaging (ce-MRI) were performed to evaluate the situation of fibroids and surrounding organs.Then fibroid's volume,hemoglobin level and the score of uterine fibroid symptom and quality of life (UFS-QOL) were recorded at pre-ablation,3-and 12-months after ablation.Side effects and complications were also assessed.Results 5 fibroids was identified as type 0,6 as type Ⅰ and 8 as type Ⅱ.8 of 19 patients had discharged necrotic tissues from vagina.Fibroid volume,hemoglobin concentration,the score of symptoms severity score(SSS) and health related quality of life (HRQL) changed from (78.75 ± 65.71)cm3,(89.50 ± 21.34)g/L,36.34 ± 17.65 and 54.38 ± 25.60 to (11.13±8.78) cm3(P =0.000),(124.60 ± 14.00)g/L (P =0.000),15.30 ± 13.58 (P =0.000) and 83.35 ± 12.28 (P =0.000) respectively.The main side effect is excessive fluid from vagina,most of the patients' fluid disappeared within 4 weeks after UPMWA,no major complications occurred after ablation.Conclusions UPMWA is a feasible,effective and safe therapy for submucous fibroids.
