CAJ | 학술논문

目的探讨实时弹性成像引导的经会阴前列腺穿刺活检在提高前列腺癌检出率中的作用.方法对108例因血清前列腺特异性抗原升高或直肠指检异常拟行前列腺穿刺活检的患者,在行实时弹性成像检查后行经直肠超声引导下经会阴穿刺活检术.穿刺方案采用10点系统穿刺加弹性成像异常处靶向穿刺,通过与前列腺穿刺病理作对照,研究追加弹性成像异常部位的靶向穿刺在提高前列腺癌检出率中的作用.结果 108例前列腺癌疑似患者经穿刺病理诊断为前列腺癌53例(53/108,49.1％).单独采用系统穿刺法的阳性率为35.2％(38/108)；通过追加对弹性成像异常发现部位的靶向穿刺能提高13.9％(15/108)穿刺阳性率(P=0.039).108例患者共穿刺1296针,其中系统穿刺共1080针,靶向穿刺共216针,靶向穿刺点阳性率为50.9％(110/216),明显高于系统穿刺点阳性率(14.1％,152/1080,P＜0.0001).结论弹性成像技术能提高前列腺癌病灶的检出率,从而提高前列腺穿刺的阳性率.
목적 탐토실시탄성성상인도적경회음전렬선천자활검재제고전렬선암검출솔중적작용.방법 대108례인혈청전렬선특이성항원승고혹직장지검이상의행전렬선천자활검적환자,재행실시탄성성상검사후행경직장초성인도하경회음천자활검술.천자방안채용10점계통천자가탄성성상이상처파향천자,통과여전렬선천자병리작대조,연구추가탄성성상이상부위적파향천자재제고전렬선암검출솔중적작용.결과 108례전렬선암의사환자경천자병리진단위전렬선암53례(53/108,49.1％).단독채용계통천자법적양성솔위35.2％(38/108)；통과추가대탄성성상이상발현부위적파향천자능제고13.9％(15/108)천자양성솔(P=0.039).108례환자공천자1296침,기중계통천자공1080침,파향천자공216침,파향천자점양성솔위50.9％(110/216),명현고우계통천자점양성솔(14.1％,152/1080,P＜0.0001).결론 탄성성상기술능제고전렬선암병조적검출솔,종이제고전렬선천자적양성솔.
Objective To determine the utility of elastography guided biopsies in men undergoing transrectal ultrasound-guided transperineal prostate biopsies.Methods A total of 108 consecutive patients suspicious for prostate cancer due to elevated serum prostate specific antigen level or abnormal digital rectal examination were enrolled in this prospective study.All patients underwent combined elastography-targeted and 10 core-systematic transperineal biopsy.The impact of elastography-targeted biopsies on the prostate cancer detection rate was analyzed in comparison with prostate biopsy pathology.Results The overall prostate cancer detection rate was 49.1％ (53/108).The prostate cancer detection rate of systematic biopsy was 35.2％(38/108).The increase in cancer detection rate by elastography-targeted biopsies was 13.9％(15/108,P =0.039).A total of 1296 cores were sampled among 108 patients,including 1080 systematic biopsy cores and 216 targeted biopsy cores.The positive rate of targeted biopsy was significantly higher than systematic biopsy (50.9％ vs 14.1％,P ＜0.0001).Conclusions Prostate cancer detection rate could be significantly improved by elastography targeted transperineal biopsy.