中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2013年
12期
1041-1044
,共4页
丁红%马姣姣%王文平%毛枫%徐晨%黄备建
丁紅%馬姣姣%王文平%毛楓%徐晨%黃備建
정홍%마교교%왕문평%모풍%서신%황비건
超声检查%肝硬化%弹性%剪切波组织定量
超聲檢查%肝硬化%彈性%剪切波組織定量
초성검사%간경화%탄성%전절파조직정량
Ultrasonography%Liver cirrhosis%Elasticity%Elastography point quantification
目的 初步分析剪切波组织定量(elastography point quantification,ElastPQ)技术评估肝弹性硬度的可行性及其主要影响因素.方法 使用Philips iU Elite超声仪对235例肝肿瘤患者的右叶肝实质进行弹性硬度检测,获得ElastPQ值,与组织病理学的肝纤维化分级(S)、炎症程度(G)和脂肪变程度以及性别和年龄因素相比较,采用多重线性回归的逐步回归方法筛选出与ElastPQ弹性测值密切相关的因素,并获得拟合方程.结果 ElastPQ弹性测值随着肝纤维化程度和炎症活动程度的加重而增大,两者相关性具有统计学意义(r =0.75,P=0.00;r=0.64,P=0.00);而脂肪变程度、性别和年龄因素与ElastPQ弹性测值无明显相关(P＞0.05).ElastPQ对肝纤维化程度和炎症活动程度的回归方程为:ElastPQ=1.205S+1.075G+4.537.结论 ElastPQ技术可有效检测肝组织弹性硬度,其中肝纤维化程度和炎症活动程度是ElastPQ弹性测值的主要影响因素.
目的 初步分析剪切波組織定量(elastography point quantification,ElastPQ)技術評估肝彈性硬度的可行性及其主要影響因素.方法 使用Philips iU Elite超聲儀對235例肝腫瘤患者的右葉肝實質進行彈性硬度檢測,穫得ElastPQ值,與組織病理學的肝纖維化分級(S)、炎癥程度(G)和脂肪變程度以及性彆和年齡因素相比較,採用多重線性迴歸的逐步迴歸方法篩選齣與ElastPQ彈性測值密切相關的因素,併穫得擬閤方程.結果 ElastPQ彈性測值隨著肝纖維化程度和炎癥活動程度的加重而增大,兩者相關性具有統計學意義(r =0.75,P=0.00;r=0.64,P=0.00);而脂肪變程度、性彆和年齡因素與ElastPQ彈性測值無明顯相關(P＞0.05).ElastPQ對肝纖維化程度和炎癥活動程度的迴歸方程為:ElastPQ=1.205S+1.075G+4.537.結論 ElastPQ技術可有效檢測肝組織彈性硬度,其中肝纖維化程度和炎癥活動程度是ElastPQ彈性測值的主要影響因素.
목적 초보분석전절파조직정량(elastography point quantification,ElastPQ)기술평고간탄성경도적가행성급기주요영향인소.방법 사용Philips iU Elite초성의대235례간종류환자적우협간실질진행탄성경도검측,획득ElastPQ치,여조직병이학적간섬유화분급(S)、염증정도(G)화지방변정도이급성별화년령인소상비교,채용다중선성회귀적축보회귀방법사선출여ElastPQ탄성측치밀절상관적인소,병획득의합방정.결과 ElastPQ탄성측치수착간섬유화정도화염증활동정도적가중이증대,량자상관성구유통계학의의(r =0.75,P=0.00;r=0.64,P=0.00);이지방변정도、성별화년령인소여ElastPQ탄성측치무명현상관(P＞0.05).ElastPQ대간섬유화정도화염증활동정도적회귀방정위:ElastPQ=1.205S+1.075G+4.537.결론 ElastPQ기술가유효검측간조직탄성경도,기중간섬유화정도화염증활동정도시ElastPQ탄성측치적주요영향인소.
Objective To preliminarily evaluate the feasibility of elastography point quantification (ElastPQ) technology in the determination of liver stiffness as well as its impact factors.Methods Amount to 235 patients with liver neoplasms underwent liver stiffness measurement in the right lobe of liver using an ultrasound scanner (iU Elite,Philips).ElastPQ values were obtained and compared with the liver fibrosis stage (S),the grade of necroinflammatory activity (G) and steatosis assessed histologically as well as gender and age.The factors related to ElastPQ values were explored by stepwise regression in multiple linear regression analysis and the regression equation was established.Results In the multiple linear regression model of ElastPQ values,liver fibrosis and necroinflammatory activity were associated with ElastPQ (P ＜ 0.05) while other factors including age,gender and hepatic steatosis had no effect on ElastPQ statistically (P ＞0.05).The equation of linear regression was ElastPQ =1.205S + 1.075G + 4.537.Conclusions ElastPQ technique is a reliably noninvasive tool in the liver stiffness measurement.Liver fibrosis and necroinflammatory activity are the main factors affecting liver stiffness measured by ElastPQ.
