CAJ | 학술논문

目的探讨声触诊组织量化(VTQ)技术对乳腺内小占位性病变的鉴别诊断价值.方法对56例69个乳腺内小占位性病变(病灶最大径≤1 cm)进行VTQ检测,测量病灶及周围正常腺体组织的剪切波速度(SWV),对比良性组与恶性组SWV的平均值(Vm)、病灶与正常腺体组织SWV之比(Vm1/Vm2),分析良、恶性病灶SWV的差异,绘制ROC曲线找出SWV预测小乳腺癌的最佳截点.结果良性组Vm、Vm1/Vm2分别为(2.93±1.32)m/s、1.79±0.63,恶性组分别为(5.65±2.63) m/s、3.61±1.35,上述参数良性组与恶性组之间差异具有统计学意义(P＜0.05).以Vm值4.43 m/s作为诊断恶性病变的截点,其灵敏度为80.5％,特异度为89.3％,准确度为92.8％;以Vm1/Vm2值2.37作为诊断恶性病变的截点,其灵敏度为76.9％,特异度为81.2％,准确度为89.9％.结论 VTQ技术对于乳腺内≤1 cm的小病灶具有较高的鉴别诊断价值.
목적 탐토성촉진조직양화(VTQ)기술대유선내소점위성병변적감별진단개치.방법 대56례69개유선내소점위성병변(병조최대경≤1 cm)진행VTQ검측,측량병조급주위정상선체조직적전절파속도(SWV),대비량성조여악성조SWV적평균치(Vm)、병조여정상선체조직SWV지비(Vm1/Vm2),분석량、악성병조SWV적차이,회제ROC곡선조출SWV예측소유선암적최가절점.결과 량성조Vm、Vm1/Vm2분별위(2.93±1.32)m/s、1.79±0.63,악성조분별위(5.65±2.63) m/s、3.61±1.35,상술삼수량성조여악성조지간차이구유통계학의의(P＜0.05).이Vm치4.43 m/s작위진단악성병변적절점,기령민도위80.5％,특이도위89.3％,준학도위92.8％;이Vm1/Vm2치2.37작위진단악성병변적절점,기령민도위76.9％,특이도위81.2％,준학도위89.9％.결론 VTQ기술대우유선내≤1 cm적소병조구유교고적감별진단개치.
Objective To evaluate the application value of virtual touch tissue quantification(VTQ) in the differential diagnosis of small breast lesions.Methods Fifty-six patients with sixty-nine small breast lesions whose largest diameter were less than or equal to 1 cm were evaluated with VTQ.The shear wave velocity (SWV) of the lesions and normal breast tissue were measured to analyze the diversity of different pathological types lesions of SWV and to find the optimal cut-off points using ROC curve to predict small breast cancer.Resuits The mean SWV(Vm) and the ratio (mean of lesions and normal tissue) of SWV (Vm1/Vm2) in benign group was (2.93 ± 1.32)m/s,1.79 ± 0.63,respectively,and that in malignant group was (5.65 ± 2.63) m/s,3.61 ± 1.35,respectively,there were statistically significant differences between benign group and malignant group (t test,P ＜0.05).The cut-off point of Vm was determined as 4.43 m/ s,the sensitivity,specificity and accuracy of diagnosing breast cancer were 80.5％,89.3％,92.8％,respectively.The cut-off point of Vm1/Vm2 was determined as 2.37,the sensitivity,specificity and accuracy of diagnosing breast cancer were 76.9％,81.2％,89.9％,respectively.Conclusions VTQ technique can provide helpful information in the differential diagnosis of small breast lesions.