CAJ | 학술논문

目的探讨三维能量多普勒超声(three-dimensional power Doppler ultrasound,3D PDUS)对宫颈癌的诊断价值.方法分析162例宫颈病变患者的3D PDUS图像,所有病例均经手术或组织活检病理证实.获得宫颈病变患者的三维血管参数,以病理结果为金标准比较良恶性病变的三维血管参数,采用ROC曲线分析三维血管参数在鉴别宫颈良恶性病变中的最佳截断值.结果宫颈良恶性病变的三维血管参数差异具有统计学意义(P＜0.0001).ROC曲线显示当选取血管指数为4.63时,曲线下面积最大达0.94,特异性和灵敏性分别为86.30％和89.10％;当血流指数为34.39时,曲线下面积最大达0.76,特异性和灵敏性分别为76.70％和73.40％;当血管血流指数为1.60时,曲线下面积最大达0.93,特异性和灵敏性分别为86.30％和87.50％.结论 3D PDUS为宫颈良恶性病变的鉴别诊断提供了一种新的无创性检查方法.
목적 탐토삼유능량다보륵초성(three-dimensional power Doppler ultrasound,3D PDUS)대궁경암적진단개치.방법 분석162례궁경병변환자적3D PDUS도상,소유병례균경수술혹조직활검병리증실.획득궁경병변환자적삼유혈관삼수,이병리결과위금표준비교량악성병변적삼유혈관삼수,채용ROC곡선분석삼유혈관삼수재감별궁경량악성병변중적최가절단치.결과 궁경량악성병변적삼유혈관삼수차이구유통계학의의(P＜0.0001).ROC곡선현시당선취혈관지수위4.63시,곡선하면적최대체0.94,특이성화령민성분별위86.30％화89.10％;당혈류지수위34.39시,곡선하면적최대체0.76,특이성화령민성분별위76.70％화73.40％;당혈관혈류지수위1.60시,곡선하면적최대체0.93,특이성화령민성분별위86.30％화87.50％.결론 3D PDUS위궁경량악성병변적감별진단제공료일충신적무창성검사방법.
Objective To evaluate the clinical value of three-dimensional power Doppler ultrasound (3D PDUS) in diagnosing cervical cancers.Methods 162 patients with cervical lesions were enrolled.All the cases were confirmed by autopsy or surgery.Vascularization index (VI),flow index (FI) and vascularization flow index(VFI) were all measured and compared.The pathological findings was taken as golden standard.ROC curve was used to find the best cut-off value.Results 3D PDUS indices of benign and malignant lesions were statistically different (P ＜0.0001).The best cut-off value of VI was 4.63 using ROC curves,the area under the curve (AUC) was 0.94,the sensitivity and specificity were 89.10％ and 86.30％,respectively.The best cut-off value of FI was 34.39 using ROC curves,AUC was 0.76,the sensitivity and specificity were 73.40％ and 76.70％,respectively.The best cut-off value of VFI was 1.60 using ROC curves,AUC was 0.93,the sensitivity and specificity were 87.50 ％ and 86.30 ％,respectively.Conclusions 3D PDUS was a new and noninvasive way for the clinical to differentiate benign and malignant cervical lesions.