CAJ | 학술논문

目的采用超声心动图研究呼吸影响心功能力学模型室间隔摆动幅度的影响因素.方法使用前期研究制作的室间隔摆动等效力学模型,改变模拟左右心室的舒张末期压力差及模拟心包腔压力,利用超声心动图观察这些压力对室间隔摆动幅度的影响.结果在恒定的模拟呼吸性胸压变化(respiratory intrathoracic pressure change,RIPC)下(0～-4 mm Hg,1 mm Hg=0.133 kPa),模拟室间隔摆动幅度随着模拟左右心室舒张末期压力差的减低而增加(2.2～17.6 mm).随着模拟心包腔压力的升高,模拟右心室和模拟左心室先后发生塌陷,室间隔摆动幅度逐渐增加,最大幅度可达22.4 mm.结论室间隔摆动作为RIPC引起呼吸性心功能变化的直接原因,其影响因素主要包括RIPC的幅度、左右心室的舒张末期压力差以及心包腔的压力.
목적 채용초성심동도연구호흡영향심공능역학모형실간격파동폭도적영향인소.방법 사용전기연구제작적실간격파동등효역학모형,개변모의좌우심실적서장말기압력차급모의심포강압력,이용초성심동도관찰저사압력대실간격파동폭도적영향.결과 재항정적모의호흡성흉압변화(respiratory intrathoracic pressure change,RIPC)하(0～-4 mm Hg,1 mm Hg=0.133 kPa),모의실간격파동폭도수착모의좌우심실서장말기압력차적감저이증가(2.2～17.6 mm).수착모의심포강압력적승고,모의우심실화모의좌심실선후발생탑함,실간격파동폭도축점증가,최대폭도가체22.4 mm.결론 실간격파동작위RIPC인기호흡성심공능변화적직접원인,기영향인소주요포괄RIPC적폭도、좌우심실적서장말기압력차이급심포강적압력.
Objective To investigate the affecting factors of interventricular septum (IVS) swing by study of the mechanical model of the respiration-driven variation of cardiac function using echocardiography.Methods In present study,the equivalent mechanical model of septal swing in previous study was used.By changing the end-diastolic pressure difference between the simulated right and left ventricles and simulated intrapericardial pressure,the subsequent influences on IVS swing using echocardiography were observed.Results Under the rhythmic respiratory intrathoracic pressure change(RIPC)(0--4 mm Hg,1 mm Hg =0.133 kPa),the swing amplitude of simulated IVS increased with decrease of the simulated end-diastolic pressure difference between the simulated right and left ventricles (2.2-17.6 mm).With increasing of the simulated intrapericardial pressure,the simulated right ventricle and left ventricle collapsed in succession,the swing amplitude of simulated IVS also increased to a maximal amplitude of 22.4 mm.Conclusions The affecting factors of IVS swing including the magnitude of RIPC,the end-diastolic pressure difference between the two ventricles and the intrapericardial pressure.