CAJ | 학술논문

目的探讨血管回声追踪(echo-tracking,ET)技术检测高尿酸血症患者颈总动脉弹性功能改变的价值.方法应用ET技术对60例正常对照者、60例单纯高尿酸血症患者(A组)、60例高尿酸合并高脂血症患者(B组)颈总动脉进行检测,获得僵硬度指数(β)、血管压力-应变弹性系数(Ep)、顺应性(AC)、扩张指数(AI)及脉搏波传导速度(PWVβ)等参数,对所得数据进行统计分析.结果与对照组比较,A组及B组患者β、Ep、PWVβ、AI均明显增高(P＜0.05),AC则明显减低(P＜0.05);与A组比较,B组患者β、Ep、PWVβ、AI均明显增高,AC则明显降低(P＜0.05).结论 ET技术能较早发现高尿酸血症及高尿酸合并高血脂患者颈总动脉弹性改变,为临床早期诊断与治疗动脉粥样硬化性病变提供重要依据.
목적 탐토혈관회성추종(echo-tracking,ET)기술검측고뇨산혈증환자경총동맥탄성공능개변적개치.방법 응용ET기술대60례정상대조자、60례단순고뇨산혈증환자(A조)、60례고뇨산합병고지혈증환자(B조)경총동맥진행검측,획득강경도지수(β)、혈관압력-응변탄성계수(Ep)、순응성(AC)、확장지수(AI)급맥박파전도속도(PWVβ)등삼수,대소득수거진행통계분석.결과 여대조조비교,A조급B조환자β、Ep、PWVβ、AI균명현증고(P＜0.05),AC칙명현감저(P＜0.05);여A조비교,B조환자β、Ep、PWVβ、AI균명현증고,AC칙명현강저(P＜0.05).결론 ET기술능교조발현고뇨산혈증급고뇨산합병고혈지환자경총동맥탄성개변,위림상조기진단여치료동맥죽양경화성병변제공중요의거.
Objective To investigate the clinical value of echo-tracking(ET) technique in evaluating the carotid elasticity in patients with hyperuricemia and hyperuricemia combined with hyperlipidemia.Methods One hundred and twenty patients with hyperuricemia were divided into two group:group of hyperuricemia (group A) and group of hyperuricemia combined with hyperlipidemia (group B).Sixty normal persons were served as the control group.ET was used to measure the carotid artery elastic modulus including stiffness parameters (β),pressure-strain elastic modulus (Ep),arterial compliance (AC),augmentation index (AI) and pulse wave conducting velocity (PWVβ).Then the statistical data were analyzed to observe the changes of each parameter.Results In the comparison of three groups,elastic function index β,Ep,PWVβ and AI in group A and group B were higher than those of control group (P ＜0.05) ;however,AC was lower than that of control group (P ＜ 0.05).Compared with group A,elastic function index β,Ep,PWVβ,AI was higher in group B,while the AC was lower than that of group B (P ＜0.05).Conclusions ET may be helpful to prevent atherosclerotic changes and to provide the basis for the clinical diagonosis and treatment atherosclerotic changes.