中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2014年
3期
227-230
,共4页
超声检查%甲状腺结节%弹性%声触诊组织量化技术
超聲檢查%甲狀腺結節%彈性%聲觸診組織量化技術
초성검사%갑상선결절%탄성%성촉진조직양화기술
Ultrasonongraphy%Thyroid nodule%Elasticity%Virtual touch tissue quantification
目的 探讨声触诊组织量化(virtual touch tissue quantification,VTQ)技术对甲状腺良恶性结节的鉴别诊断价值及影响因素.方法 运用VTQ技术对127例患者的甲状腺结节及结节周围同一深度的正常甲状腺组织进行定量检测,检测结果以纵向剪切波速度值(SWV)表示,记录甲状腺结节SWV最大值(Vmax)、最小值(Vmin)以及结节周围组织的SWV值(Vn),计算甲状腺结节SWV平均值(Vm)以及Vm与Vn的比值(Vm/n),对良恶性结节及不同病理类型结节SWV值进行对比分析.绘制ROC曲线,对VTQ技术诊断效能进行评价.结果 甲状腺恶性结节的Vmax、Vmin、Vm、Vm/n[分别为(4.61±2.65)m/s、(2.74±2.23)m/s、(2.99±0.82)m/s、(1.69±1.07)m/s]均明显高于良性结节[分别为(2.78±0.96)m/s、(1.75±0.60)m/s、(2.31±0.38) m/s、(0.94±0.23)m/s,均P＜0.01].甲状腺乳头状癌SWV值高于结节性甲状腺肿、甲状腺腺瘤以及桥本甲状腺炎(P＜0.05).桥本甲状腺炎SWV值高于甲状腺腺瘤及结节性甲状腺肿(P＜0.05).甲状腺腺瘤与结节性甲状腺肿SWV值差异无统计学意义(P＞0.05).对比以上4组不同SWV值ROC曲线下面积,结果显示Vm对于甲状腺良恶性结节具有较高的诊断价值.以Vm值2.48 m/s为最佳界值点时VTQ对于甲状腺良恶性结节的诊断价值最大,对应灵敏性、特异性分别为97％、81％.结论 VTQ技术可对甲状腺结节硬度进行定量评估,为甲状腺良恶性结节的鉴别诊断提供重要信息.
目的 探討聲觸診組織量化(virtual touch tissue quantification,VTQ)技術對甲狀腺良噁性結節的鑒彆診斷價值及影響因素.方法 運用VTQ技術對127例患者的甲狀腺結節及結節週圍同一深度的正常甲狀腺組織進行定量檢測,檢測結果以縱嚮剪切波速度值(SWV)錶示,記錄甲狀腺結節SWV最大值(Vmax)、最小值(Vmin)以及結節週圍組織的SWV值(Vn),計算甲狀腺結節SWV平均值(Vm)以及Vm與Vn的比值(Vm/n),對良噁性結節及不同病理類型結節SWV值進行對比分析.繪製ROC麯線,對VTQ技術診斷效能進行評價.結果 甲狀腺噁性結節的Vmax、Vmin、Vm、Vm/n[分彆為(4.61±2.65)m/s、(2.74±2.23)m/s、(2.99±0.82)m/s、(1.69±1.07)m/s]均明顯高于良性結節[分彆為(2.78±0.96)m/s、(1.75±0.60)m/s、(2.31±0.38) m/s、(0.94±0.23)m/s,均P＜0.01].甲狀腺乳頭狀癌SWV值高于結節性甲狀腺腫、甲狀腺腺瘤以及橋本甲狀腺炎(P＜0.05).橋本甲狀腺炎SWV值高于甲狀腺腺瘤及結節性甲狀腺腫(P＜0.05).甲狀腺腺瘤與結節性甲狀腺腫SWV值差異無統計學意義(P＞0.05).對比以上4組不同SWV值ROC麯線下麵積,結果顯示Vm對于甲狀腺良噁性結節具有較高的診斷價值.以Vm值2.48 m/s為最佳界值點時VTQ對于甲狀腺良噁性結節的診斷價值最大,對應靈敏性、特異性分彆為97％、81％.結論 VTQ技術可對甲狀腺結節硬度進行定量評估,為甲狀腺良噁性結節的鑒彆診斷提供重要信息.
목적 탐토성촉진조직양화(virtual touch tissue quantification,VTQ)기술대갑상선량악성결절적감별진단개치급영향인소.방법 운용VTQ기술대127례환자적갑상선결절급결절주위동일심도적정상갑상선조직진행정량검측,검측결과이종향전절파속도치(SWV)표시,기록갑상선결절SWV최대치(Vmax)、최소치(Vmin)이급결절주위조직적SWV치(Vn),계산갑상선결절SWV평균치(Vm)이급Vm여Vn적비치(Vm/n),대량악성결절급불동병리류형결절SWV치진행대비분석.회제ROC곡선,대VTQ기술진단효능진행평개.결과 갑상선악성결절적Vmax、Vmin、Vm、Vm/n[분별위(4.61±2.65)m/s、(2.74±2.23)m/s、(2.99±0.82)m/s、(1.69±1.07)m/s]균명현고우량성결절[분별위(2.78±0.96)m/s、(1.75±0.60)m/s、(2.31±0.38) m/s、(0.94±0.23)m/s,균P＜0.01].갑상선유두상암SWV치고우결절성갑상선종、갑상선선류이급교본갑상선염(P＜0.05).교본갑상선염SWV치고우갑상선선류급결절성갑상선종(P＜0.05).갑상선선류여결절성갑상선종SWV치차이무통계학의의(P＞0.05).대비이상4조불동SWV치ROC곡선하면적,결과현시Vm대우갑상선량악성결절구유교고적진단개치.이Vm치2.48 m/s위최가계치점시VTQ대우갑상선량악성결절적진단개치최대,대응령민성、특이성분별위97％、81％.결론 VTQ기술가대갑상선결절경도진행정량평고,위갑상선량악성결절적감별진단제공중요신식.
Objective To investigate the evaluation of virtual touch tissue quantification(VTQ)in differential diagnosis of thyroid benign and malignant nodules and its influence factors.Methods 127 patients with thyroid lesions and its adjacent normal thyroid tissue at the same depth were examined with VTQ.Test results were performed by shear wave velocity value (SWV) on the long axis dimension of the nodules.The maximum(Vmax),minimum(Vmin) value of SWV of thyroid lesions and the SWV(Vn) value of surrounding normal tissue were recorded.The mean value of SWV (Vm) and the ratio of Vm and Vn (Vm/n) were calculated.SWV value of benign and malignant nodules and different pathological types of nodules were analyzed.Receiver-operating characteristic curve(ROC) was drawn to assess the diagnostic efficiency.Results The Vmax,Vmin,Vm,Vm/n of malignant lesions [(4.61 ± 2.65) m/s,(2.74 ± 2.23) m/s,(2.99 ± 0.82)m/s,(1.69 ± 1.07)m/s,respectively] were obviously higher than that of benign nodules [(2.78 ± 0.96)m/s,(1.75 ± 0.60)m/s,(2.31 ± 0.38)m/s,(0.94 ± 0.23)m/s,respectively,P ＜0.01].The SWV value of thyroid papillary carcinoma was higher than that of nodular goiter,thyroid adenoma and Hashimoto's thyroiditis(P ＜0.05).The SWV value of Hashimoto's thyroiditis was higher than that of thyroid adenoma and nodular goiter (P ＜ 0.05).No significant differences of SWV value were found between thyroid adenoma and nodular goiter (P ＞ 0.05).Contrast the area under the receiver-operating curves above four groups of different SWV values,the results showed that Vm had the highest diagnostic value in diagnosis of benign and malignant thyroid nodules.When the best cut-off point of Vm was 2.48 m/s,the diagnostic value was highest and the sensitivity and specificity were 97％ and 81 ％.Conclusions VTQ could be used to quantify and evaluate the hardness of thyroid nodules and provided important value for the differential diagnosis of benign and malignant thyroid nodules.
