CAJ | 학술논문

目的应用二维斑点追踪技术及组织多普勒技术分别评价移植心脏左、右室纵向收缩功能.方法 56例心脏移植患者,根据心内膜心肌活检及长期临床随访结果分为无排异组(A组)和排异组(B组),随机入选36例健康志愿者归入C组,测量左室射血分数(LVEF)、肺动脉收缩压、三尖瓣瓣环位移(TAPSE)和三尖瓣瓣环收缩期速度(TA-S')等指标.应用Qlab 9.0软件分析获得左室整体纵向应变值(global longitudinal strain,GLS).结果 B组较C组LVEF降低(P＜0.01).三组间GLS、TAPSE及TA-S'值比较差异均有统计学意义(P均＜0.01),B组＜A组＜C组;GLS与LVEF、TAPSE、TA-S'有较好的负相关性(r分别为-0.64,-0.69,-0.71,P均＜0.01).结论心脏移植患者左、右室纵向收缩功能均有不同程度降低.
목적 응용이유반점추종기술급조직다보륵기술분별평개이식심장좌、우실종향수축공능.방법 56례심장이식환자,근거심내막심기활검급장기림상수방결과분위무배이조(A조)화배이조(B조),수궤입선36례건강지원자귀입C조,측량좌실사혈분수(LVEF)、폐동맥수축압、삼첨판판배위이(TAPSE)화삼첨판판배수축기속도(TA-S')등지표.응용Qlab 9.0연건분석획득좌실정체종향응변치(global longitudinal strain,GLS).결과 B조교C조LVEF강저(P＜0.01).삼조간GLS、TAPSE급TA-S'치비교차이균유통계학의의(P균＜0.01),B조＜A조＜C조;GLS여LVEF、TAPSE、TA-S'유교호적부상관성(r분별위-0.64,-0.69,-0.71,P균＜0.01).결론 심장이식환자좌、우실종향수축공능균유불동정도강저.
Objective To investigate longitudinal systolic function of transplanted heart using two dimensional speckle tracking echocardiography and tissue Doppler imaging.Methods 56 consecutive patients with heart transplant were recruited,according to myocardial biopsy and 1 year's follow up,they were divided into non-rejection group (group A) and rejection group (group B).36 healthy controls (group C) were also randomly recruited.Left ventricular ejection fraction (LVEF),pulmonary arterial systolic pressure,tricuspid annular plane systolic excursion (TAPSE),tricuspid annular plane systolic velocity (TAS') and global longitudinal strain (GLS) were calculated via Qlab 9.0 analysis software offline.Results Compared with group C,LVEF was reduced in group B (P ＜0.01).Differences of GLS,TAPSE,and TA-S' among groups were all statistically significant (P ＜0.01),group B＜group A＜ group C.LVEF,TAPSE and TA-S' were correlated with GLS (r =-0.64,r =-0.69,r =-0.71 ; all P ＜ 0.01).Conclusions Left and right ventricles were a functional unity,the systolic function of which was impaired in patients with heart transplant.