中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2014年
5期
419-422
,共4页
苏昆仑%徐海滨%涂美琳%张正贤%何俊玲%胡祖健%杨欧欧%罗华%杨慧芬
囌昆崙%徐海濱%塗美琳%張正賢%何俊玲%鬍祖健%楊歐歐%囉華%楊慧芬
소곤륜%서해빈%도미림%장정현%하준령%호조건%양구구%라화%양혜분
超声检查%乳腺肿瘤%病理学%弹性成像
超聲檢查%乳腺腫瘤%病理學%彈性成像
초성검사%유선종류%병이학%탄성성상
Ultrasonography%Breast neoplasms%Pathology%Elastography
目的 探讨浸润性乳腺癌超声弹性成像与病理的相关性.方法 经手术病理证实的96例单病灶浸润性乳腺癌患者,术前应用传统超声和弹性成像硬度评分法评价病灶.比较不同弹性成像评分组手术标本的浸润病灶大小、肿瘤类型、组织学分级、脉管侵犯状态、淋巴结状态、Ki67和Her-2表达等组织学指标.Mann-WhitneyU检验和Spearman相关系数分析超声弹性成像和病理的相关性.结果 不同弹性成像评分组的弹性成像评分与高组织学分级(r=0.476,P＜0.01)、淋巴结转移(z=4.506,P＜0.01)、脉管侵犯(z=3.795,P＜0.01)以及Ki67阳性(z=2.593,P=0.01)正相关,与肿瘤类型(r=-0.277,P＜0.01)负相关.结论 超声弹性成像上硬度高的乳腺癌病理学上预后不佳.
目的 探討浸潤性乳腺癌超聲彈性成像與病理的相關性.方法 經手術病理證實的96例單病竈浸潤性乳腺癌患者,術前應用傳統超聲和彈性成像硬度評分法評價病竈.比較不同彈性成像評分組手術標本的浸潤病竈大小、腫瘤類型、組織學分級、脈管侵犯狀態、淋巴結狀態、Ki67和Her-2錶達等組織學指標.Mann-WhitneyU檢驗和Spearman相關繫數分析超聲彈性成像和病理的相關性.結果 不同彈性成像評分組的彈性成像評分與高組織學分級(r=0.476,P＜0.01)、淋巴結轉移(z=4.506,P＜0.01)、脈管侵犯(z=3.795,P＜0.01)以及Ki67暘性(z=2.593,P=0.01)正相關,與腫瘤類型(r=-0.277,P＜0.01)負相關.結論 超聲彈性成像上硬度高的乳腺癌病理學上預後不佳.
목적 탐토침윤성유선암초성탄성성상여병리적상관성.방법 경수술병리증실적96례단병조침윤성유선암환자,술전응용전통초성화탄성성상경도평분법평개병조.비교불동탄성성상평분조수술표본적침윤병조대소、종류류형、조직학분급、맥관침범상태、림파결상태、Ki67화Her-2표체등조직학지표.Mann-WhitneyU검험화Spearman상관계수분석초성탄성성상화병리적상관성.결과 불동탄성성상평분조적탄성성상평분여고조직학분급(r=0.476,P＜0.01)、림파결전이(z=4.506,P＜0.01)、맥관침범(z=3.795,P＜0.01)이급Ki67양성(z=2.593,P=0.01)정상관,여종류류형(r=-0.277,P＜0.01)부상관.결론 초성탄성성상상경도고적유선암병이학상예후불가.
Objective To investigation the correlation between ultrasonography elastography (UE) and the pathology of invasive breast cancer.Methods A total of 96 patients with solid lesions of breast cancer undergoing preoperative UE and surgery were included.Lesions were evaluated by conventional ultrasound and elastographic strain scores,which were classified into five grades.In different UE score groups,histologic findings following surgery were used for comparison,namely invasive size,tumor type,histologic grade,vascular invasion status,lymph node status,Ki67 and Her-2 expression.Relationship between UE scores and pathology was investigated by using Mann-Whitney U test and Spearman correlation coefficients.Results High histologic grade (r =0.476,P ＜0.01),lymph node involvement (z =4.506,P ＜0.01),vascular invasion (z =3.795,P ＜0.01) and Ki67 positive (z =2.593,P =0.01) all showed statistically signifcant positive association with UE scores.There was a negative correlation between tumor type (r =-0.277,P ＜0.01) and UE scores.Conclusions Invasive breast cancers with higher UE scores had poorer prognostic features of pathology.
