CAJ | 학술논문

目的探讨剪切波弹性成像(shear wave elastography,SWE)技术在弥漫性甲状腺疾病中的应用价值.方法 41例弥漫性甲状腺疾病患者[Graves病(GD) 16例,桥本甲状腺炎(HT)16例,亚急性甲状腺炎(SAT)9例]和30例健康志愿者,行SWE检测并比较病例组和正常组甲状腺组织弹性模量的平均值(Emean)、最小值(Emin)及最大值(Emax).结果分别与正常组[Emean(15.7±2.5)kPa、Emin(11.6±2.4)kPa及Emax (20.2±3.0)kPa]比较,GD组Emean[(20.4±4.7) kPa]、Emin[(14.4±3.8)kPa]及Emax[(27.8±7.3)kPa],HT组Emean[(18.4±5.0)kPa]及Emax[(25.2±5.8)kPa],SAT组Emean[(11.0±2.9)kPa]及Emin[(6.0±2.7) kPa]的差异有统计学意义(P=0.001,0.007,0.001;P =0.045,0.001;P =0.000,0.000).SAT组与GD、HT组各指标比较差异均有统计学意义(P均＜0.05).HT组与GD组各指标比较差异无统计学意义(P＞0.05).结论 SWE可定量测量甲状腺组织的弹性模量值,获得客观的组织硬度信息,为弥漫性甲状腺疾病的鉴别诊断提供依据.
목적 탐토전절파탄성성상(shear wave elastography,SWE)기술재미만성갑상선질병중적응용개치.방법 41례미만성갑상선질병환자[Graves병(GD) 16례,교본갑상선염(HT)16례,아급성갑상선염(SAT)9례]화30례건강지원자,행SWE검측병비교병례조화정상조갑상선조직탄성모량적평균치(Emean)、최소치(Emin)급최대치(Emax).결과 분별여정상조[Emean(15.7±2.5)kPa、Emin(11.6±2.4)kPa급Emax (20.2±3.0)kPa]비교,GD조Emean[(20.4±4.7) kPa]、Emin[(14.4±3.8)kPa]급Emax[(27.8±7.3)kPa],HT조Emean[(18.4±5.0)kPa]급Emax[(25.2±5.8)kPa],SAT조Emean[(11.0±2.9)kPa]급Emin[(6.0±2.7) kPa]적차이유통계학의의(P=0.001,0.007,0.001;P =0.045,0.001;P =0.000,0.000).SAT조여GD、HT조각지표비교차이균유통계학의의(P균＜0.05).HT조여GD조각지표비교차이무통계학의의(P＞0.05).결론 SWE가정량측량갑상선조직적탄성모량치,획득객관적조직경도신식,위미만성갑상선질병적감별진단제공의거.
Objective To explore the value of shear wave elastography (SWE) in diffuse thyroid disease.Methods The elastic modulus were detected by SWE in 41cases of diffuse thyroid disease [including 16 cases of Graves' disease (GD),16 cases of Hashimoto' s thyroiditis (HT) and 9 cases of subacute thyroiditis(SAT)] and 30 cases of healthy volunteers.The elastic modulus,including Emean,Emin and Emax,were measured and compared.Results Compared with the normal group[Emean(15.7-± 2.5)kPa,Emin(11.6 ± 2.4)kPa and Emax (20.2 ± 3.0)kPa],the Emean[(20.4 ± 4.7)kPa],Emin[(14.4-± 3.8)kPa] and Emax [(27.8 ± 7.3)kPa] of GD,the Emean [(18.4-± 5.0)kPa] and Emax [(25.2 ± 5.8)kPa] of HT,and the Emean[(11.0 ± 2.9)kPa] and Emin [(6.0 ± 2.7)kPa] of the SAT were different significantly(P =0.001,0.007,0.001 ; P =0.045,0.001 ; P =0.000,0.000).There were significant differences between the SAT and the other two groups,namely GD and HT (P ＜0.05).Such differences,however,were not found between GD and HT (P ＞0.05).Conclusions SWE can be used to measure the elastic modulus of the thyroid tissue quantitatively and objectively,serving as a useful technique to predict the diffuse thyroid disease.