CAJ | 학술논문

目的探讨二维超声及弹性应变率比值(SR)在甲状腺结节(FNA)细针穿刺诊断中的作用.方法回顾性分析196个甲状腺结节二维超声及弹性成像与FNA诊断结果,以手术病理为金标准,应用ROC曲线分析SR的最佳临界值;对年龄、结节回声、钙化和SR进行Logistic回归分析,评价各变量的诊断效能;试分析SR在穿刺前后的应用策略.结果恶性结节与良性结节的SR差异有统计学意义,SR的最佳临界点为0.5(敏感性91.7％,特异性90.2％,准确性90.8％);多因素分析按OR值高低依次为SR、年龄、回声、钙化;SR在穿刺前可以筛选出无穿刺必要的结节,在穿刺后可以提高FNA诊断甲状腺肿瘤良恶性的敏感性、特异性和准确性.结论 SR诊断甲状腺恶性肿瘤有良好的应用价值,可以减少不必要的穿刺,并对穿刺结果进行补充诊断.
목적 탐토이유초성급탄성응변솔비치(SR)재갑상선결절(FNA)세침천자진단중적작용.방법 회고성분석196개갑상선결절이유초성급탄성성상여FNA진단결과,이수술병리위금표준,응용ROC곡선분석SR적최가림계치;대년령、결절회성、개화화SR진행Logistic회귀분석,평개각변량적진단효능;시분석SR재천자전후적응용책략.결과 악성결절여량성결절적SR차이유통계학의의,SR적최가림계점위0.5(민감성91.7％,특이성90.2％,준학성90.8％);다인소분석안OR치고저의차위SR、년령、회성、개화;SR재천자전가이사선출무천자필요적결절,재천자후가이제고FNA진단갑상선종류량악성적민감성、특이성화준학성.결론 SR진단갑상선악성종류유량호적응용개치,가이감소불필요적천자,병대천자결과진행보충진단.
Objective To evaluate the value of 2D ultrasound and elastic strain ratio (SR) in diagnosis of thyroid nodule by fine needle aspiration (FNA).Methods 196 thyroid nodules were analyzed retrospectively with 2D ultrasound,elastography and FNA results,pathology results as the golden standard.A receiver operating characteristic (ROC) curve was used to identify the best cut-off point of SR.The Logistic regression analysis was used to evaluate the variables effectiveness on age,nodule echo,calcification and SR.Tried to discuss how to use SR before or after US-FNA in diagnosis of thyroid nodule.Results The SR of the malignant nodules group was significantly different from the benign nodules group,and the best cut-off point was 0.5 with sensitivity 91.7％,specificity 90.2 ％ and accuracy 90.8 ％.The Logistic analysis results were SR,age,echo,calcification according to the odds ratio.SR can screened nodules without puncture necessary before FNA,and increase the FNA sensitivity,specificity and accuracy after FNA.Conclusions SR has good application value in diagnosis thyroid malignant tumor.SR can reduce unnecessary FNA and make a supplementary diagnosis of FNA.