中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2014年
7期
590-593
,共4页
王福建%徐芳%张义林%徐栋%来乐祥
王福建%徐芳%張義林%徐棟%來樂祥
왕복건%서방%장의림%서동%래악상
超声检查,多普勒,彩色%糖尿病视网膜病变%血红蛋白A,糖基化
超聲檢查,多普勒,綵色%糖尿病視網膜病變%血紅蛋白A,糖基化
초성검사,다보륵,채색%당뇨병시망막병변%혈홍단백A,당기화
Ultrasonography,Doppler,color%Diabetic retinopathy%Hemoglobin A,glycosylated
目的 通过分析糖尿病眼底动脉血流参数与糖化血红蛋白(GHb)之间的相关性,探讨糖尿病眼底动脉血流动力学评估的临床价值.方法 糖尿病患者98例(196只眼),其中治疗前49例(98只眼),治疗后49例(98只眼);正常对照组100例(200只眼).检测各受检者GHb,应用彩色多普勒超声检测眼动脉(OA)、视网膜中央动脉(CRA)及睫状后动脉(PCA),比较糖尿病组与正常对照组眼底动脉血流参数,并分析眼底动脉血流参数与GHb的关系.结果 糖尿病组跟底动脉的收缩期最大血流速度(PSV)和舒张末期血流速度(EDV)均下降,阻力指数(RI)增加,与正常对照组比较差异均有统计学意义(P<0.05),糖尿病组治疗前后比较差异有统计学意义(P<0.05);GHb与眼底动脉PSV、EDV呈负相关(PSD∶rPCA=-0.491,rCRA=-0.482,rOA=-0.602;EDV∶rPCA=-0.427,rCRA=-0.489,rOA=-0.509),与RI呈正相关(rPCA=0.464,rCRA=0.523,rOA=0.611).结论 糖尿病眼底动脉血流动力学的评估可以为糖尿病视网膜灌注情况及功能改变提供有用的信息,对评价糖尿病视网膜的病程有重要的临床价值.
目的 通過分析糖尿病眼底動脈血流參數與糖化血紅蛋白(GHb)之間的相關性,探討糖尿病眼底動脈血流動力學評估的臨床價值.方法 糖尿病患者98例(196隻眼),其中治療前49例(98隻眼),治療後49例(98隻眼);正常對照組100例(200隻眼).檢測各受檢者GHb,應用綵色多普勒超聲檢測眼動脈(OA)、視網膜中央動脈(CRA)及睫狀後動脈(PCA),比較糖尿病組與正常對照組眼底動脈血流參數,併分析眼底動脈血流參數與GHb的關繫.結果 糖尿病組跟底動脈的收縮期最大血流速度(PSV)和舒張末期血流速度(EDV)均下降,阻力指數(RI)增加,與正常對照組比較差異均有統計學意義(P<0.05),糖尿病組治療前後比較差異有統計學意義(P<0.05);GHb與眼底動脈PSV、EDV呈負相關(PSD∶rPCA=-0.491,rCRA=-0.482,rOA=-0.602;EDV∶rPCA=-0.427,rCRA=-0.489,rOA=-0.509),與RI呈正相關(rPCA=0.464,rCRA=0.523,rOA=0.611).結論 糖尿病眼底動脈血流動力學的評估可以為糖尿病視網膜灌註情況及功能改變提供有用的信息,對評價糖尿病視網膜的病程有重要的臨床價值.
목적 통과분석당뇨병안저동맥혈류삼수여당화혈홍단백(GHb)지간적상관성,탐토당뇨병안저동맥혈류동역학평고적림상개치.방법 당뇨병환자98례(196지안),기중치료전49례(98지안),치료후49례(98지안);정상대조조100례(200지안).검측각수검자GHb,응용채색다보륵초성검측안동맥(OA)、시망막중앙동맥(CRA)급첩상후동맥(PCA),비교당뇨병조여정상대조조안저동맥혈류삼수,병분석안저동맥혈류삼수여GHb적관계.결과 당뇨병조근저동맥적수축기최대혈류속도(PSV)화서장말기혈류속도(EDV)균하강,조력지수(RI)증가,여정상대조조비교차이균유통계학의의(P<0.05),당뇨병조치료전후비교차이유통계학의의(P<0.05);GHb여안저동맥PSV、EDV정부상관(PSD∶rPCA=-0.491,rCRA=-0.482,rOA=-0.602;EDV∶rPCA=-0.427,rCRA=-0.489,rOA=-0.509),여RI정정상관(rPCA=0.464,rCRA=0.523,rOA=0.611).결론 당뇨병안저동맥혈류동역학적평고가이위당뇨병시망막관주정황급공능개변제공유용적신식,대평개당뇨병시망막적병정유중요적림상개치.
Objective To explore the value of ocular fundus artery hemodynamics in diabetes by the correlation study between ocular fundus artery and glycosylated hemoglobin(GHb).Methods GHb was checked in 98 patients (196 eyes) in diabetes,including 49 cases (98 eyes) before treatment and 49 cases (98 eyes) after treatment,and normal group of 100 cases (200 eyes)An all cases,color Doppler ultrasonography was used for monitorind ophthalmic artery(OA),central retinal artery(CRA) and posterior ciliary artery (PCA).Finally,the differences of the parameters vauels of the the OA,CRA,and PCA between diabetic and normal group were studied in order to find out the relationship with GHb.Results Of 98 patients in diabetes,peak systolic velocity and end diastolic velocity of fundus artery decreased,resistance index increased(RI).There was significant difference between diabetic and normal group(P <0.05),and a significant difference was exited between diabetic group before and after treatment(P <0.05).GHb were negatively correlated with the velocity of fundus artery,and positively correlated with RI.Conclusions Evaluation of ocular fundus artery hemodynamics in diabetes can provide useful information for diabetic retinal perfusion and function change.For evaluation of diabetic retinal disease,it is of great value in clinical application.