CAJ | 학술논문

目的探讨超声造影定量分析技术在移植肾急性排异中的应用价值.方法 102例肾移植患者,包括移植肾功能正常组67例,急性排异组35例.常规超声测量段间、叶间动脉的收缩期峰值流速(PSV)及阻力指数(RI),超声造影定量分析移植肾整体灌注曲线形态,然后选取皮质、髓质、段间动脉及叶间动脉四个感兴趣区,软件生成定量参数:造影剂上升时间(RT)、达峰时间(TTP)、平均渡越时间(mTT).计算皮质、髓质与叶间动脉的造影剂灌注时间差⊿RT皮-叶、⊿RT髓-叶、⊿TTP皮-叶、⊿TTP髓-叶及⊿mTT皮-叶、⊿mTT髓-时.结果叶间动脉PSV在两组闻差异有统计学意义(P＜0.0S).移植肾整体灌注曲线形态、⊿RT皮-叶及⊿TTP皮-叶在两组间差异有统计学意义(P＜0.05).结论超声造影定量分析技术可为移植肾急性排异提供定量诊断方法.
목적 탐토초성조영정량분석기술재이식신급성배이중적응용개치.방법 102례신이식환자,포괄이식신공능정상조67례,급성배이조35례.상규초성측량단간、협간동맥적수축기봉치류속(PSV)급조력지수(RI),초성조영정량분석이식신정체관주곡선형태,연후선취피질、수질、단간동맥급협간동맥사개감흥취구,연건생성정량삼수:조영제상승시간(RT)、체봉시간(TTP)、평균도월시간(mTT).계산피질、수질여협간동맥적조영제관주시간차⊿RT피-협、⊿RT수-협、⊿TTP피-협、⊿TTP수-협급⊿mTT피-협、⊿mTT수-시.결과 협간동맥PSV재량조문차이유통계학의의(P＜0.0S).이식신정체관주곡선형태、⊿RT피-협급⊿TTP피-협재량조간차이유통계학의의(P＜0.05).결론 초성조영정량분석기술가위이식신급성배이제공정량진단방법.
Objective To study the value of quantitative analysis of contrast-enhanced ultrasound in diagnosing acute rejection of kidney graft.Methods Sixty-seven patients with normal kidney grafts and thirty-five patients with acute rejection were recruited.In conventional ultrasound,the peak systolic velocity (PSV) and resistance index (RI) of segmental artery and interlobar artery were measured.In quantitative analysis of contrast-enhanced ultrasound,four regions of interest including renal cortex,medulla,segmental artery and interlobar artery were drew and three parameters including rising time(RT),time to peak(TTP) and mean transit time(mTT) were obtained.In addition,the difference in RT,TTP and mTT between the renal cortex and interlobar artery,as well as medulla and interlobar artery were calculated.Results The differences of PSV in interlobar artery between the two groups were statistically significant (P ＜0.05).The time-intensity curves of the whole kidney grafts,and the difference in RT and TTP between the renal cortex and interlobar artery were statistically different between two groups (P ＜0.05).Conclasions Quantitative analysis of contrast-enhanced ultrasound proved a quantitative method for diagnosing kidney allograft acute rejection.