中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2014年
7期
609-613
,共5页
戴蓓蓓%任芸芸%孙莉%孔凡斌%归绥琪%邱冬%周毓青
戴蓓蓓%任蕓蕓%孫莉%孔凡斌%歸綏琪%邱鼕%週毓青
대배배%임예예%손리%공범빈%귀수기%구동%주육청
超声检查%多囊卵巢综合征%肥胖%内分泌学
超聲檢查%多囊卵巢綜閤徵%肥胖%內分泌學
초성검사%다낭란소종합정%비반%내분비학
Ultrasonography%Polycystic ovary syndrome%Obesity%Endocrinology
目的 比较不同临床表现的多囊卵巢综合征(PCOS)患者超声参数与内分泌指标特征.方法 将149例PCOS患者分为肥胖型PCOS组(OB-PCOS组)和非肥胖型PCOS组(NOB-PCOS组),测量并比较两组卵泡数、平均卵巢直径、卵巢体积、间质体积和卵泡体积以及血管化指数(Ⅵ)、血流指数(FI)、血管化-血流指数(VFI).检测并比较两组黄体生成素(LH)、卵泡刺激素(FSH)、孕酮(P)、雌二醇(E2)、总睾酮(T)、泌乳素(PRL)、性激素结合球蛋白(SHBG)、游离雄激素指数(FAI)、血糖(FPG)、血浆胰岛素(FINS)、稳态模型指数(HOMA-IR).分析超声参数和内分泌指标的相关性.结果 OB-PCOS组卵巢直径、卵泡数、卵巢体积、间质体积、卵泡体积、FI和VFI、FINS、HOMA-IR、FAI较NOB-PCOS组增大,FSH、SHBG较NOB-PCOS组降低,差异有统计学意义(P<0.05或0.01).OB-PCOS组卵泡数与FSH呈正相关(r=0.771,P<0.01),卵巢体积、间质体积、FI、VFI与HOMA-IR呈正相关(r分别为0.412、0.842、0.389、0.415,P<0.05或0.01),FI与FAI呈正相关(r=0.812,P<0.01).在NOB-PCOS组中,患者卵巢卵泡数与FAI呈正相关(r=0.472,P<0.05),卵巢体积与FAI呈正相关(r=0.552,P<0.05).结论 肥胖型与非肥胖型PCOS有不同的超声参数和内分泌指标特征.
目的 比較不同臨床錶現的多囊卵巢綜閤徵(PCOS)患者超聲參數與內分泌指標特徵.方法 將149例PCOS患者分為肥胖型PCOS組(OB-PCOS組)和非肥胖型PCOS組(NOB-PCOS組),測量併比較兩組卵泡數、平均卵巢直徑、卵巢體積、間質體積和卵泡體積以及血管化指數(Ⅵ)、血流指數(FI)、血管化-血流指數(VFI).檢測併比較兩組黃體生成素(LH)、卵泡刺激素(FSH)、孕酮(P)、雌二醇(E2)、總睪酮(T)、泌乳素(PRL)、性激素結閤毬蛋白(SHBG)、遊離雄激素指數(FAI)、血糖(FPG)、血漿胰島素(FINS)、穩態模型指數(HOMA-IR).分析超聲參數和內分泌指標的相關性.結果 OB-PCOS組卵巢直徑、卵泡數、卵巢體積、間質體積、卵泡體積、FI和VFI、FINS、HOMA-IR、FAI較NOB-PCOS組增大,FSH、SHBG較NOB-PCOS組降低,差異有統計學意義(P<0.05或0.01).OB-PCOS組卵泡數與FSH呈正相關(r=0.771,P<0.01),卵巢體積、間質體積、FI、VFI與HOMA-IR呈正相關(r分彆為0.412、0.842、0.389、0.415,P<0.05或0.01),FI與FAI呈正相關(r=0.812,P<0.01).在NOB-PCOS組中,患者卵巢卵泡數與FAI呈正相關(r=0.472,P<0.05),卵巢體積與FAI呈正相關(r=0.552,P<0.05).結論 肥胖型與非肥胖型PCOS有不同的超聲參數和內分泌指標特徵.
목적 비교불동림상표현적다낭란소종합정(PCOS)환자초성삼수여내분비지표특정.방법 장149례PCOS환자분위비반형PCOS조(OB-PCOS조)화비비반형PCOS조(NOB-PCOS조),측량병비교량조란포수、평균란소직경、란소체적、간질체적화란포체적이급혈관화지수(Ⅵ)、혈류지수(FI)、혈관화-혈류지수(VFI).검측병비교량조황체생성소(LH)、란포자격소(FSH)、잉동(P)、자이순(E2)、총고동(T)、비유소(PRL)、성격소결합구단백(SHBG)、유리웅격소지수(FAI)、혈당(FPG)、혈장이도소(FINS)、은태모형지수(HOMA-IR).분석초성삼수화내분비지표적상관성.결과 OB-PCOS조란소직경、란포수、란소체적、간질체적、란포체적、FI화VFI、FINS、HOMA-IR、FAI교NOB-PCOS조증대,FSH、SHBG교NOB-PCOS조강저,차이유통계학의의(P<0.05혹0.01).OB-PCOS조란포수여FSH정정상관(r=0.771,P<0.01),란소체적、간질체적、FI、VFI여HOMA-IR정정상관(r분별위0.412、0.842、0.389、0.415,P<0.05혹0.01),FI여FAI정정상관(r=0.812,P<0.01).재NOB-PCOS조중,환자란소란포수여FAI정정상관(r=0.472,P<0.05),란소체적여FAI정정상관(r=0.552,P<0.05).결론 비반형여비비반형PCOS유불동적초성삼수화내분비지표특정.
Objective To study the relationship of three-dimensional power Doppler ultrasonographic parameters and endocrine profile in different symptoms of patients with polycystic ovary syndrome(PCOS).Methods One hundred and forty nine women with PCOS were divided into two groups,which included obese PCOS(OB-PCOS) group and non-obese PCOS (NOB-PCOS) group.The ultrasonic parameters such as follicle number,ovarian average diameter,ovarian volume,stromal volume,follicle volume,vascularization index(Ⅵ),flow index(FI),vascularization flow index(VFI) were measured and compared.Serum levels of luteinizing hormone (LH),follicle stimulating hormone (FSH),progesterone (P),estradiol (E2),testosterone(T),prolactin (PRL),sex hormone binding globulin (SHBG),free androgen index (FAI),fasting plasma glucose (FPG),fasting insulin (FINS),homeostasis model assessment-IR(HOMA-IR) were also measured and compared.The correlation of the ultrasonic parameters and hormonal factors were analyzed.Results The follicle number,ovarian average diameter,ovarian volume,stromal volume,follicle volume,FI and VFI,FINS,HOMA-IR,FAI of OB-PCOS were significantly higher than those of NOB-PCOS (P <0.01 or 0.05),the FSH,SHBG were significantly lower than those of NOB-PCOS (P <0.05 or 0.01).In OB-PCOS group,the follicle number was significantly associated with FSH(r =0.771,P <0.01).The ovarian volume,stromal volume,FI and VFI were significantly associated with HOMA-IR(r =0.412,0.842,0.389,0.415,P <0.05 or 0.01),FI was significantly associated with FAI (r =0.812,P <0.01).In NOB-PCOS group,the follicle number,ovarian volume were significantly associated with FAI(r =0.472,0.552,P <0.05)..Conclusions There are some different characters in ultrasonography and endocrine parameters between obese and non-obese PCOS patients.