CAJ | 학술논문

目的调查中国妇科门诊40 ～ 60岁患者的绝经相关特征.方法 2008年3月至9月对中国14家医院妇科门诊40 ～ 60岁患者采用统一问卷进行面对面调查.调查其绝经过渡期、出现绝经症状和自然绝经的年龄以及对激素补充治疗的认知程度.结果共有1641例患者完成了问卷调查.进入绝经过渡期、出现绝经症状和自然绝经的年龄分别为(47±4)、(46±4)和(49±3)岁.78.43％(1287/1641)的患者在绝经过渡期存在绝经相关症状,以轻、中度为主；最常见的5种绝经相关症状是乏力(71.48％,1173/1641)、易激动(68.68％,1127/1641)、失眠(67.65％,1110/1641)、骨关节和肌肉痛(64.11％,1052/1641)及潮热(57.90％,950/1641).在绝经过程的不同亚阶段,出现绝经相关症状的程度不同,以绝经过渡期晚期和绝经后期最为明显,出现中、重度绝经相关症状者分别占59.1％(189/320)和51.1％(291/570).76.5％(750/981)的患者在月经变化的过程中出现了绝经相关症状,17.5％(172/981)的患者是先有绝经相关症状后发生月经改变,6.0％(59/981)的患者在绝经后才出现绝经相关症状.在到医院就诊的患者中激素补充治疗的知晓率达56.39％(733/1300),信息来源主要是妇产科医师,占54.08％(703/1300).结论到医院就诊的绝经过渡期患者大部分有绝经相关症状,但以轻、中度为主；尽管大多数妇女是在月经变化的过程中出现绝经相关症状,但仍有一部分妇女是先有绝经相关症状后发生月经改变.
목적 조사중국부과문진40 ～ 60세환자적절경상관특정.방법 2008년3월지9월대중국14가의원부과문진40 ～ 60세환자채용통일문권진행면대면조사.조사기절경과도기、출현절경증상화자연절경적년령이급대격소보충치료적인지정도.결과 공유1641례환자완성료문권조사.진입절경과도기、출현절경증상화자연절경적년령분별위(47±4)、(46±4)화(49±3)세.78.43％(1287/1641)적환자재절경과도기존재절경상관증상,이경、중도위주；최상견적5충절경상관증상시핍력(71.48％,1173/1641)、역격동(68.68％,1127/1641)、실면(67.65％,1110/1641)、골관절화기육통(64.11％,1052/1641)급조열(57.90％,950/1641).재절경과정적불동아계단,출현절경상관증상적정도불동,이절경과도기만기화절경후기최위명현,출현중、중도절경상관증상자분별점59.1％(189/320)화51.1％(291/570).76.5％(750/981)적환자재월경변화적과정중출현료절경상관증상,17.5％(172/981)적환자시선유절경상관증상후발생월경개변,6.0％(59/981)적환자재절경후재출현절경상관증상.재도의원취진적환자중격소보충치료적지효솔체56.39％(733/1300),신식래원주요시부산과의사,점54.08％(703/1300).결론 도의원취진적절경과도기환자대부분유절경상관증상,단이경、중도위주；진관대다수부녀시재월경변화적과정중출현절경상관증상,단잉유일부분부녀시선유절경상관증상후발생월경개변.
Objective To investigate the characteristics of menopause of Chinese women with the age of 40-60 years concerning gynecologic clinics in China.Methods From Mar.2008 to Sept.2008,a face-to-face questionnaire was conducted in gynecological clinic in perimenopausal and postmenopausal women in 14 hospitals in China,which included general demographic data,menstrual change process,climacteric symptoms and knowledge about menopause.Modified Kupperman index were used to evaluate climacteric symptoms during the recent week and awareness of hormonal replacement therapy were studied.Results A total of 1641 women were investigated.The ages of onset of menopause transition,climacteric symptoms and natural menopause were (47±4),(46±4),(49±3) years old respectively.Climacteric symptoms could be found in 78.43％ (1287/1641) women during menopausal transition,which were mainly mild to moderate symptoms.The top 5 symptoms were fatigue and weakness (71.48％,1173/1641),irritability (68.68％,1127/1641),insomnia (67.65％,1110/1641),muscle and joint pain (64.11％,1052/1641) and hot flush (57.90％,950/1641).The climacteric symptoms were not constant during menopausal transition,usually more severe in late transition and postmenopausal periods,during which the moderate and severe symptoms were 59.1％ (189/320) and 51.1％ (291/570) respectively.Although most symptoms primarily appeared along with menstruation change,there are about 17.5％ (172/981) patients experienced climacteric symptoms before menstruation change occurrence.There were 56.39％ (733/1300)women had ever heard (mostly from gynecologist) about hormone replacement therapy from Obstetrician and Gynecologist.Conclusions Most of the women during menopausal transition had climacteric symptoms,usually mild and moderate ones.Although most symptoms primarily appeared along with menstruation change,there are other patients' experienced climacteric symptoms before menstruation change occurrence.