CAJ | 학술논문

目的通过对怀疑受到电离辐射照射的医疗工作人员进行外周血淋巴细胞染色体畸变分析,探讨可能的受影响因素.方法某医院检验科工作人员7名,男性1名,女性6名.他们工作室的楼下是医院CT室,工作室和CT室间的楼板为厚度约6 cm的普通预制板.采用常规法,对7名人员外周血淋巴细胞染色体畸变进行分析.结果 4例女性工作人员外周血中检测到双着丝粒体(dic),dic率为0.40％～ 1.60％,明显高于dic的自发率(0.03％,x2=36.79,P＜0.05)；在所有工作人员中均检测到易位畸变,易位率在0.33％～1.20％之间,明显高于易位的自发率(0.01％,X2=42.90,P＜0.05).结论推测这些工作人员受到过量电离辐射照射.
목적 통과대부의수도전리복사조사적의료공작인원진행외주혈림파세포염색체기변분석,탐토가능적수영향인소.방법 모의원검험과공작인원7명,남성1명,녀성6명.타문공작실적루하시의원CT실,공작실화CT실간적루판위후도약6 cm적보통예제판.채용상규법,대7명인원외주혈림파세포염색체기변진행분석.결과 4례녀성공작인원외주혈중검측도쌍착사립체(dic),dic솔위0.40％～ 1.60％,명현고우dic적자발솔(0.03％,x2=36.79,P＜0.05)；재소유공작인원중균검측도역위기변,역위솔재0.33％～1.20％지간,명현고우역위적자발솔(0.01％,X2=42.90,P＜0.05).결론 추측저사공작인원수도과량전리복사조사.
Objective To investigate the chromosomal aberrations in seven medical staffs suspected with exposure to ionizing radiation and to speculate its possible causation.Methods The hospital staffs,including 6 females and 1 male,worked in a clinical laboratory where a CT room was located downstairs.The thickness of precast slab between these two rooms was 6 cm.Peripheral blood lymphocytes of seven staffs were examined for conventional chromosomal aberrations.Results The frequencies of dicentrics in the peripheral lymphocytes of 4 females were from 0.40％ to 1.60％ that was significantly higher than the spontaneous frequency of dicentrics (0.03％,x2 =36.79,P ＜ 0.05).The translocation was observed in the lymphocytes from all subjects with frequencies from 0.33％ to 1.20％,obviously higher than its spontaneous frequency of 0.01％ (x2 =42.90,P ＜ 0.05).Conclusion These staffs suffer from ionizing radiation.