CAJ | 학술논문

目的将滑轨CT图像引导技术应用于胸中上段食管癌放疗,计算在线CT图像引导和非在线CT引导这两种因素各自的靶区外扩边距.方法 100例胸中上段食管癌计划进行调强放疗的患者,每次放疗前进行CT扫描并与计划CT图像配准比较分析,获得分次间摆位误差数据,并在线修正;根据系统选样法选取50例患者,增加治疗后的CT扫描以分析修正后的误差、治疗中的位移、分次内肿瘤(GTV)位移.结果与非在线CT图像引导相比,采用在线CT图像引导使得靶区外扩边距在左右、头脚、腹背方向由8.8、9.1和6.1 mm降低到4.1、4.5和4.3 mm.结论应用在线CT图像引导能显著提高靶区精准度,缩小靶区外扩边距.
목적 장활궤CT도상인도기술응용우흉중상단식관암방료,계산재선CT도상인도화비재선CT인도저량충인소각자적파구외확변거.방법 100례흉중상단식관암계화진행조강방료적환자,매차방료전진행CT소묘병여계화CT도상배준비교분석,획득분차간파위오차수거,병재선수정;근거계통선양법선취50례환자,증가치료후적CT소묘이분석수정후적오차、치료중적위이、분차내종류(GTV)위이.결과 여비재선CT도상인도상비,채용재선CT도상인도사득파구외확변거재좌우、두각、복배방향유8.8、9.1화6.1 mm강저도4.1、4.5화4.3 mm.결론 응용재선CT도상인도능현저제고파구정준도,축소파구외확변거.
Objective To compare the clinical target volume (CTV) expanding margins in the mid-and upper-thoracic esophageal carcinoma during radiotherapy measured with and without online image guidance technique by CT on rail.Methods 100 patients with mid-and upper-thoracic esophageal carcinoma undergoing intensity modulated radiotherapy received CT scanning.Image registration was conducted between the scanning results and the planned CT images,thus set-up error data were acquired and got on-line correction.Fifty patients were randomly selected to undergo additional post-treatment CT scanningso as to analyze the revised residuals,displacement during treatment,and infra-fraction GTV shifts.Results Compared to the radiotherapy without CT-based image guidance,the CTV expanding margins obtained with CT-based image guidance was reduced significantly from 9.1,8.8 and 6.1 mm to 4.1,4.5 and 4.3 mm in the left-right,head-feet,and belly-back directions respectively.Conclusions The on-line image-guided technology significantly improves the accuracy of target and reduces the CTV expanding margins.