中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2014年
1期
59-61
,共3页
张宏涛%唐富龙%吴立丽%高贞%孙美玲%赵静%王泽阳%王娟
張宏濤%唐富龍%吳立麗%高貞%孫美玲%趙靜%王澤暘%王娟
장굉도%당부룡%오립려%고정%손미령%조정%왕택양%왕연
125I粒子%近距离治疗%剂量
125I粒子%近距離治療%劑量
125I입자%근거리치료%제량
125I seed%Brachytherapy%Dose
目的 观察125I粒子植入时,计算机治疗计划系统(TPS)软件中计算点阵网格大小对剂量计算精度的影响.方法 采用随机数字表法抽取10例粒子植入患者的验证计划,将点阵网格调整为128×128、96×96、64×64、32 ×32共4组,在粒子数目、位置、活度及靶区大小相同的条件下,应用TPS计算每个计划的剂量,分别得出4组D90、V90、V100及V150,并计算D90的误差.结果 128×128、96×96、64×64、32×32 4组点阵网格D90平均数分别为(7 178.8 ±2 237.7)、(7 072.7±2 240.8)、(6889.1±2305.5)、(6 351.0±2 515.7) cGy;D90误差百分比分别为(0.74±0.6)％、(-0.89±2.2)％、(-3.85 ±4.7)％、(-10.46±4.8)％,组间差异有统计学意义(F=8.95,P ＜0.05).4组点阵网格V90分别为(93.12±0.32)％、(92.75 ±0.29)％、(91.87±1.28)％、(88.06±5.06)％,组间差异有统计学意义(F=7.85,P＜0.05);V100分别为(90.21±0.14)％、(89.67±0.64)％、(88.68±1.80)％、(84.10±6.56)％,组间差异有统计学意义(F=6.64,P＜0.05);V150分别为(73.48±3.49)％、(72.66±3.96)％、(71.33±4.83)％、(65.41±9.49)％,组间差异有统计学意义(F=3.90,P＜0.05).结论 计算点阵网格大小明显影响TPS计算剂量的准确性,在保证运算速度同时应尽量应用128×128的计算点阵网格.
目的 觀察125I粒子植入時,計算機治療計劃繫統(TPS)軟件中計算點陣網格大小對劑量計算精度的影響.方法 採用隨機數字錶法抽取10例粒子植入患者的驗證計劃,將點陣網格調整為128×128、96×96、64×64、32 ×32共4組,在粒子數目、位置、活度及靶區大小相同的條件下,應用TPS計算每箇計劃的劑量,分彆得齣4組D90、V90、V100及V150,併計算D90的誤差.結果 128×128、96×96、64×64、32×32 4組點陣網格D90平均數分彆為(7 178.8 ±2 237.7)、(7 072.7±2 240.8)、(6889.1±2305.5)、(6 351.0±2 515.7) cGy;D90誤差百分比分彆為(0.74±0.6)％、(-0.89±2.2)％、(-3.85 ±4.7)％、(-10.46±4.8)％,組間差異有統計學意義(F=8.95,P ＜0.05).4組點陣網格V90分彆為(93.12±0.32)％、(92.75 ±0.29)％、(91.87±1.28)％、(88.06±5.06)％,組間差異有統計學意義(F=7.85,P＜0.05);V100分彆為(90.21±0.14)％、(89.67±0.64)％、(88.68±1.80)％、(84.10±6.56)％,組間差異有統計學意義(F=6.64,P＜0.05);V150分彆為(73.48±3.49)％、(72.66±3.96)％、(71.33±4.83)％、(65.41±9.49)％,組間差異有統計學意義(F=3.90,P＜0.05).結論 計算點陣網格大小明顯影響TPS計算劑量的準確性,在保證運算速度同時應儘量應用128×128的計算點陣網格.
목적 관찰125I입자식입시,계산궤치료계화계통(TPS)연건중계산점진망격대소대제량계산정도적영향.방법 채용수궤수자표법추취10례입자식입환자적험증계화,장점진망격조정위128×128、96×96、64×64、32 ×32공4조,재입자수목、위치、활도급파구대소상동적조건하,응용TPS계산매개계화적제량,분별득출4조D90、V90、V100급V150,병계산D90적오차.결과 128×128、96×96、64×64、32×32 4조점진망격D90평균수분별위(7 178.8 ±2 237.7)、(7 072.7±2 240.8)、(6889.1±2305.5)、(6 351.0±2 515.7) cGy;D90오차백분비분별위(0.74±0.6)％、(-0.89±2.2)％、(-3.85 ±4.7)％、(-10.46±4.8)％,조간차이유통계학의의(F=8.95,P ＜0.05).4조점진망격V90분별위(93.12±0.32)％、(92.75 ±0.29)％、(91.87±1.28)％、(88.06±5.06)％,조간차이유통계학의의(F=7.85,P＜0.05);V100분별위(90.21±0.14)％、(89.67±0.64)％、(88.68±1.80)％、(84.10±6.56)％,조간차이유통계학의의(F=6.64,P＜0.05);V150분별위(73.48±3.49)％、(72.66±3.96)％、(71.33±4.83)％、(65.41±9.49)％,조간차이유통계학의의(F=3.90,P＜0.05).결론 계산점진망격대소명현영향TPS계산제량적준학성,재보증운산속도동시응진량응용128×128적계산점진망격.
Objective To study the influence of TPS calculation grid on the dose calculation accuracy for 125I seed implantation.Methods Ten verification plans were selected randomly.Calculating grids were modulated into four groups:128 × 128,96 × 96,64 × 64 and 32 × 32.Under the conditions of same seeds number,location,activity and target volume,the doses resulting from every plan were calculated using TPS to obtain D90,V90,V100 and V150.Data were grouped into A,B,C and D by means of the calculating grid of 128 × 128,96 × 96,64 × 64 and 32 × 32.The percentage errors of four groups were calculated.Results The arithmetic mean D90 of group A,B,C and D were (7 178.8 ± 2 237.7),(7 072.7 ±2 240.8),(6 889.1 ±2 305.5) and (6 351.0 ±2 515.7)cGy,respectively.The arithmetic mean of percentage errors of the four groups were (0.74 ± 0.6) ％,(-0.89 ± 2.2) ％,(-3.85 ± 4.7) ％ and (-10.46 ±4.8)％ (F=8.95,P ＜0.05).The V90 of group A,B,C and D were (93.12 ± 0.32)％,(92.75 ±0.29)％,(91.87±1.28)％ and (88.06 ±5.06)％ (F=7.85,P＜0.05).The V100ofgroupA,B,C and D were (90.21 ±0.14)％,(89.67 ±0.64)％,(88.68 ± 1.80)％ and (84.10±6.56)％(F=6.64,P＜0.05).The V150 of group A,B,C and D were (73.48 ±3.49)％,(72.66±3.96)％,(71.33±4.83)％ and (65.41 ±9.49)％ (F=3.90,P＜0.05).Conclusions The dose calculating accuracy of 125I seeds implantation is influenced significantly by TPS calculating grid.The calculating grid of 128 × 128 should be used as long as the calculating speed is not reduced.
