CAJ | 학술논문

目的探讨食管癌初治患者IMRT前PET-CT显像对其治疗方案的影响.方法回顾分析60例经食管镜检证实的食管癌患者,患者均为初次治疗,经常规影像检查后拟行IMRT.放疗前行PET-CT显像,观察是否有分期和治疗方案改变.结果与常规影像比,PET-CT显像使12例患者分期发生改变(2例T期上调、6例N期上调、2例N期下调、2例M期上调).3例患者由于新发现较多的远处转移,治疗方案由放疗改为化疗.PET-CT检查导致20例患者靶区改变,其中16例因发现更多转移淋巴结使靶体积增大,4例则排除了淋巴结转移使靶区缩小.结论 PET-CT对食管癌区域淋巴结和远处转移诊断有一定优势,有助提高分期准确性,改变了部分患者治疗决策方案.
목적 탐토식관암초치환자IMRT전PET-CT현상대기치료방안적영향.방법 회고분석60례경식관경검증실적식관암환자,환자균위초차치료,경상규영상검사후의행IMRT.방료전행PET-CT현상,관찰시부유분기화치료방안개변.결과 여상규영상비,PET-CT현상사12례환자분기발생개변(2례T기상조、6례N기상조、2례N기하조、2례M기상조).3례환자유우신발현교다적원처전이,치료방안유방료개위화료.PET-CT검사도치20례환자파구개변,기중16례인발현경다전이림파결사파체적증대,4례칙배제료림파결전이사파구축소.결론 PET-CT대식관암구역림파결화원처전이진단유일정우세,유조제고분기준학성,개변료부분환자치료결책방안.
Objective To investigate the impact of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) before intensity-modulated radiotherapy (IMRT) on treatment regimen in patients with newly diagnosed esophageal cancer.Methods A retrospective analysis was performed on 60 patients with esophageal cancer newly diagnosed by esophagoscopy,who underwent conventional imaging examination and IMRT.All patients underwent PET/CT before IMRT to evaluate whether the staging and treatment regimen would be changed.Results PET/CT provided additional information and led to changes in staging in 12 patients (2 patients with increased T stage,6 patients with increased N stage,2 patients with decreased N stage,and 2 patients with increased M stage).In addition,PET/CT changed management from radiotherapy to chemotherapy in 3 patients for detecting more distant metastases.The use of PET/CT led to changed target volumes in 20 of 57 patients:16 patients showed an increase in gross target volume or clinical target volume for more positive lymph nodes detected,and 4 patients exhibited target volume reduction for some positive lymph nodes excluded.Conclusions PET/CT has advantages in detecting positive local lymph nodes and distant metastases and helping improve the accuracy of staging in patients with esophageal cancer,which may lead to change in treatment regimen.