CAJ | 학술논문

目的探讨11C-MET PET-CT和MRI图像对脑胶质瘤GTV确定的差异.方法选取6例经病理证实为胶质瘤患者的术前MRI及11C-MET PET-CT图像,分别由我科5位医师在两种图像资料上勾画GTV,比较两者差异.结果在MRI11C-MET PET-CT上勾画的GTV体积相似(P=0.917),GTV变异系数也相似(P =0.600).勾画的GTV重合度最大为73.0％、最小为51.8％.方差分析显示不同勾画者之间在两种图像资料上勾画的GTV相似(P =0.709),但PET-CT组GTV最大差值为27.66 cm3,而MRI组的为40.37 cm3.结论 MRI与PET-CT显示的肿瘤边界存在差异,不同勾画者勾画的GTV相似,PET-CT组的GTV最大差值较MRI组的小,11C-MET PET-CT显示GTV较为直观.
목적 탐토11C-MET PET-CT화MRI도상대뇌효질류GTV학정적차이.방법 선취6례경병리증실위효질류환자적술전MRI급11C-MET PET-CT도상,분별유아과5위의사재량충도상자료상구화GTV,비교량자차이.결과 재MRI11C-MET PET-CT상구화적GTV체적상사(P=0.917),GTV변이계수야상사(P =0.600).구화적GTV중합도최대위73.0％、최소위51.8％.방차분석현시불동구화자지간재량충도상자료상구화적GTV상사(P =0.709),단PET-CT조GTV최대차치위27.66 cm3,이MRI조적위40.37 cm3.결론 MRI여PET-CT현시적종류변계존재차이,불동구화자구화적GTV상사,PET-CT조적GTV최대차치교MRI조적소,11C-MET PET-CT현시GTV교위직관.
Objective To evaluate the difference between MRI and 11C-MET PET-CT for gross tumor volume (GTV) delineation in the precision radiotherapy for gliomas.Methods Six patients with a pathologically confirmed diagnosis of gliomas were selected for target delineation.Five physicians in our department were called to delineate the GTV based on the preoperative MRI and 11C-MET PET-CT images of these patients.The GTVs based on the two methods were compared.Results There was no significant difference between the GTVs based on MRI and 11C-MET PET-CT (P =0.917),and their coefficients of variation were also similar (P =0.600).The coincidences of GTVs were different among the patients,with a maximum value of 73.0％ and a minimum value of 51.8％.GTV showed no significant difference when defined by different physicians on MRI and PET-CT (P =0.709) ; the biggest difference was 27.66 cm3 on PET-CT and 40.37 cm3 on MRI.Conclusions The boundaries of gliomas defined on MRI and PET-CT are different.The GTVs delineated by different physicians on MRI and PET-CT are similar,and the biggest difference on PET-CT is smaller than that on MRI,which suggests that 11C-MET PET-CT is a more direct way for displaying GTV.