中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2014年
4期
294-296
,共3页
非小细胞肺癌%肺腺癌%肺鳞癌%淋巴结转移
非小細胞肺癌%肺腺癌%肺鱗癌%淋巴結轉移
비소세포폐암%폐선암%폐린암%림파결전이
Non-small cell lung cancer%Lung adenocarcinoma%Lung squamous carcinoma%Lymph node metastasis
目的 探索NSCLC胸内淋巴结的转移规律,为放疗靶区勾画提供理论依据.方法 回顾分析314例NSCLC术后患者的临床资料,重点探讨胸内淋巴结的分布特点、转移范围,及其与肿瘤大小、病理类型及原发部位的关系.x2检验组间差别.结果 NSCLC术后4、5、7、10、11组淋巴结转移率均＞12％,1、2、3、6、8、9组均＜12％.原发肿瘤部位与N2组淋巴结转移相近(P=0.102).而原发灶T3、T4期出现N2组淋巴结转移概率较T1、T2期明显增高(17.0％∶11.6％,P=0.002),腺癌较鳞癌N2组更易转移(34.5％∶23.2％,P=0.008).结论 T3、T4期NSCLC及腺癌患者术后放疗靶区勾画时应着重关注第4、5、7、10、11组淋巴结.
目的 探索NSCLC胸內淋巴結的轉移規律,為放療靶區勾畫提供理論依據.方法 迴顧分析314例NSCLC術後患者的臨床資料,重點探討胸內淋巴結的分佈特點、轉移範圍,及其與腫瘤大小、病理類型及原髮部位的關繫.x2檢驗組間差彆.結果 NSCLC術後4、5、7、10、11組淋巴結轉移率均＞12％,1、2、3、6、8、9組均＜12％.原髮腫瘤部位與N2組淋巴結轉移相近(P=0.102).而原髮竈T3、T4期齣現N2組淋巴結轉移概率較T1、T2期明顯增高(17.0％∶11.6％,P=0.002),腺癌較鱗癌N2組更易轉移(34.5％∶23.2％,P=0.008).結論 T3、T4期NSCLC及腺癌患者術後放療靶區勾畫時應著重關註第4、5、7、10、11組淋巴結.
목적 탐색NSCLC흉내림파결적전이규률,위방료파구구화제공이론의거.방법 회고분석314례NSCLC술후환자적림상자료,중점탐토흉내림파결적분포특점、전이범위,급기여종류대소、병리류형급원발부위적관계.x2검험조간차별.결과 NSCLC술후4、5、7、10、11조림파결전이솔균＞12％,1、2、3、6、8、9조균＜12％.원발종류부위여N2조림파결전이상근(P=0.102).이원발조T3、T4기출현N2조림파결전이개솔교T1、T2기명현증고(17.0％∶11.6％,P=0.002),선암교린암N2조경역전이(34.5％∶23.2％,P=0.008).결론 T3、T4기NSCLC급선암환자술후방료파구구화시응착중관주제4、5、7、10、11조림파결.
Objective To investigate the patterns of intrathoracic lymph node metastasis in nonsmall cell lung cancer (NSCLC) and to provide a theoretical basis for the delineation of radiotherapy target volume.Methods A retrospective analysis was performed on the clinical data of 314 NSCLC patients after operation.Our focus was to investigate the distribution characteristics and metastatic extent of intrathoracic lymph nodes and their relationship with tumor size,pathological type,and primary site.Comparisons between groups were made by one-way analysis of variance.Results The frequencies of metastases to lymph nodes at stations 4,5,7,10,and 11 were all above 12％,while those at stations 1,2,3,6,8,and 9 were all below 12％.The lymph node metastasis rate was similar on the primary tumor site (P =0.102).The patients with T3 and T4 NSCLC had a significantly higher frequency of N2 lymph node metastasis than those with T1 and T2 NSCLC (17.0％ vs.11.6％,P =0.002) ;the patients with adenocarcinoma had a significantly higher frequency of N2 lymph node metastasis than those with squamous cell carcinoma (34.5 ％ vs.23.2％,P =0.008).Conclusions For patients with T3 and T4 NSCLC of adenocarcinoma subtype,we should highlight the lymph nodes at stations 4,5,7,10,and 11 when delineating the radiotherapy target volume after operation.
