中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2014年
4期
340-343
,共4页
李晓玉%周继丹%钟仁明%李安%李帅
李曉玉%週繼丹%鐘仁明%李安%李帥
리효옥%주계단%종인명%리안%리수
鼻咽肿瘤/放射疗法%体层摄影术,X线计算机,锥形束%图像配准
鼻嚥腫瘤/放射療法%體層攝影術,X線計算機,錐形束%圖像配準
비인종류/방사요법%체층섭영술,X선계산궤,추형속%도상배준
Nasopharyngeal neoplasms/radiotherapy%Tomography,X-ray computed,conebeam%Image registration
目的 比较千伏级CBCT引导下鼻咽癌IMRT中不同图像配准方式对配准结果的影响.方法 搜集2012-2013年24例鼻咽癌IMRT患者560次治疗前初次摆位的千伏级CBCT图像做离线配准分析.分别选取骨与灰度的平移误差加旋转误差配准方式(BoneT+R与GreyT+R),以及单纯灰度平移误差配准方式(GreyT),并对配准结果行配对t检验.结果 BoneT+R在左右、上下、前后方向的靶区中心平移误差与旋转误差分别为(-0.11 ±1.35)、(0.40±2.09)、(0.95±1.56) mm与1.06°±0.67°、0.01°±1.28°、0.92°±1.00°;GreyT+R的平移误差与旋转误差分别为(-0.02±1.06)、(0.68±1.92)、(0.81±1.46)mm与0.85°±0.61°、-0.05°±1.32°、0.91°±0.72°;GreyT的平移误差分别为(0.58±1.02)、(0.52±1.89)、(0.44±1.43) mm.除BoneT+R与GreyT+R旋转误差在上下、前后方向上相近外(P =0.05、0.62),其余均不同(P=0.00～0.01).结论 用千伏级CBCT引导鼻咽癌IMRT时,在三维方向上的配准结果因图像配准方式不同而有差别.选择自动配准方式时,若要纠正旋转误差建议选择GreyT+R方式;不纠正旋转误差时建议可先选择GreyT+R方式观察有否旋转误差＞2°或3°(视各放疗中心要求而定),若有则需重新摆位,若无则重新选择GreyT方式,必要时辅以手动修正.
目的 比較韆伏級CBCT引導下鼻嚥癌IMRT中不同圖像配準方式對配準結果的影響.方法 搜集2012-2013年24例鼻嚥癌IMRT患者560次治療前初次襬位的韆伏級CBCT圖像做離線配準分析.分彆選取骨與灰度的平移誤差加鏇轉誤差配準方式(BoneT+R與GreyT+R),以及單純灰度平移誤差配準方式(GreyT),併對配準結果行配對t檢驗.結果 BoneT+R在左右、上下、前後方嚮的靶區中心平移誤差與鏇轉誤差分彆為(-0.11 ±1.35)、(0.40±2.09)、(0.95±1.56) mm與1.06°±0.67°、0.01°±1.28°、0.92°±1.00°;GreyT+R的平移誤差與鏇轉誤差分彆為(-0.02±1.06)、(0.68±1.92)、(0.81±1.46)mm與0.85°±0.61°、-0.05°±1.32°、0.91°±0.72°;GreyT的平移誤差分彆為(0.58±1.02)、(0.52±1.89)、(0.44±1.43) mm.除BoneT+R與GreyT+R鏇轉誤差在上下、前後方嚮上相近外(P =0.05、0.62),其餘均不同(P=0.00～0.01).結論 用韆伏級CBCT引導鼻嚥癌IMRT時,在三維方嚮上的配準結果因圖像配準方式不同而有差彆.選擇自動配準方式時,若要糾正鏇轉誤差建議選擇GreyT+R方式;不糾正鏇轉誤差時建議可先選擇GreyT+R方式觀察有否鏇轉誤差＞2°或3°(視各放療中心要求而定),若有則需重新襬位,若無則重新選擇GreyT方式,必要時輔以手動脩正.
목적 비교천복급CBCT인도하비인암IMRT중불동도상배준방식대배준결과적영향.방법 수집2012-2013년24례비인암IMRT환자560차치료전초차파위적천복급CBCT도상주리선배준분석.분별선취골여회도적평이오차가선전오차배준방식(BoneT+R여GreyT+R),이급단순회도평이오차배준방식(GreyT),병대배준결과행배대t검험.결과 BoneT+R재좌우、상하、전후방향적파구중심평이오차여선전오차분별위(-0.11 ±1.35)、(0.40±2.09)、(0.95±1.56) mm여1.06°±0.67°、0.01°±1.28°、0.92°±1.00°;GreyT+R적평이오차여선전오차분별위(-0.02±1.06)、(0.68±1.92)、(0.81±1.46)mm여0.85°±0.61°、-0.05°±1.32°、0.91°±0.72°;GreyT적평이오차분별위(0.58±1.02)、(0.52±1.89)、(0.44±1.43) mm.제BoneT+R여GreyT+R선전오차재상하、전후방향상상근외(P =0.05、0.62),기여균불동(P=0.00～0.01).결론 용천복급CBCT인도비인암IMRT시,재삼유방향상적배준결과인도상배준방식불동이유차별.선택자동배준방식시,약요규정선전오차건의선택GreyT+R방식;불규정선전오차시건의가선선택GreyT+R방식관찰유부선전오차＞2°혹3°(시각방료중심요구이정),약유칙수중신파위,약무칙중신선택GreyT방식,필요시보이수동수정.
Objective To compare the results of three different registration methods in the kilovolt CBCT guided IMRT for nasopharyngeal cancer (NPC).Methods Total 560 CBCT images of 24 NPC patients who received kilovolt CBCT guided IMRT were analyzed off line.Three registration methods were used for alignment between CBCT and planning CT,including translational and rotational errors for bone and grey (BoneT + R,GreyT+ R),only translational errors for grey (GreyT).The registration results were analyzed by mean paired t-test respectively.Results With method BoneT+R,the translational errors on x,y and z axes were (-0.11 ± 1.35) mm,(0.40 ± 2.09) mm and (0.95 ± 1.56) mm and the rotational errors were 1.06° ±0.67°,0.01° ± 1.28° and 0.92° ± 1.00° respectively.With GreyT+R,the translational errors on x,y and z axes were (-0.02 ± 1.06) mm,(0.68 ± 1.92) mm and (0.81 ± 1.46) mm and the rotational errors were 0.85° ±0.61°,-0.05° ± 1.32° and 0.91° ±0.72° respectively.With GreyT,the translational errors on x,y and z axes were (0.58 ± 1.02),(0.52 ± 1.89) and (0.44 ± 1.43) mm.The results of compared mean t-test for different registration methods groups have significant difference (P =0.00-0.01) except for the rotational errors on y and z axes between BoneT+R and GreyT+R (P =0.05,0.62).Conclusions There have different alignment errors when different registration methods used for NPC kilovolt CBCT guided radiotherapy.If there have correct methods for rotation errors,GreyT+R registration method may be a better choice.In opposite,GreyT+R registration method would be used firstly to verify whether the rotational error ＞ 2°or 3°.If the rotational error ＞ 2°or 3°,the patient should be re-setup.If not,according to these alignment results,the GreyT method,manual method would be used to compensate the translational errors.
