CAJ | 학술논문

目的探讨胰腺印戎细胞癌的诊治.方法回顾性分析天津肿瘤医院收治的、经手术病理证实的胰腺印戒细胞癌患者临床资料.结果共4例胰腺印戒细胞癌病例,临床表现无特异性,主要症状有:上腹胀痛,可伴背痛和皮肤、巩膜黄染.1例患者癌抗原19-9和癌胚抗原增高.4例患者均行姑息性短路手术,术中行活检.平均生存期为2.8个月.结论胰腺印戒细胞癌发病率低,预后差.手术是目前有效的治疗手段,但切除率低.化疗效果有待进一步证实.
목적 탐토이선인융세포암적진치.방법 회고성분석천진종류의원수치적、경수술병리증실적이선인계세포암환자림상자료.결과 공4례이선인계세포암병례,림상표현무특이성,주요증상유:상복창통,가반배통화피부、공막황염.1례환자암항원19-9화암배항원증고.4례환자균행고식성단로수술,술중행활검.평균생존기위2.8개월.결론 이선인계세포암발병솔저,예후차.수술시목전유효적치료수단,단절제솔저.화료효과유대진일보증실.
Objective To analyze the investigation and treatment of signet ring cell carcinoma of pancreas.Method The clinical data of patients with histopathologically confirmed signet ring cell carcinoma of pancreas were analyzed retrospectively.Results There were 4 patients with signet ring cell carcinoma.There was no patient who presented with a typical carcinoid syndrome.Most patients presented with upper abdominal pain,backache or jaundice caused by bile duct obstruction.In one patient CA19-9 and CEA were raised.All patients received palliative biliary bypass and needle biopsy of the tumour.The median survival was 2.8 months.Conclusions Pancreatic signet ring cell carcinoma is a rare disease with poor prognosis.Surgery is the only effective treatment but the resectability rate is low.Whether this tumour responds to chemotherapy requires further studies.