中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2013年
5期
337-339
,共3页
游志坚%王在国%胡夏荣%林志强%俞武生%叶振伟
遊誌堅%王在國%鬍夏榮%林誌彊%俞武生%葉振偉
유지견%왕재국%호하영%림지강%유무생%협진위
肝癌%膈肌部分切除%膈肌侵犯%手术
肝癌%膈肌部分切除%膈肌侵犯%手術
간암%격기부분절제%격기침범%수술
Hepatocellular carcinoma%Partial diaphragmatic resection%Diaphragmatic invasion%Surgery
目的 探讨肝癌合并右膈肌部分切除的适应证、手术方法、术中应注意的问题,总结肝癌侵犯右膈肌的外科处理经验.方法 对广东省东莞市人民医院1998年9月至2008年9月收治的27例肝癌合并右膈肌部分切除患者的临床资料进行回顾性分析.结果 全部病例手术均获得成功.切除肿瘤直径5.0~15.0(平均8.5)cm,合并切除右膈肌面积9.0~50(平均28.5)cm2,手术时间110~250(平均165)min,失血量450~2600(平均870)ml.术后病理证实膈肌侵犯者9例(33.3%).术后全部病例均见少量右胸积液.其他并发症包括慢性肝功能不全4例及术后早期出血、上消化道出血、胆汁瘘、膈下感染各1例.所有患者经相应处理后均康复出院,无围手术期死亡病例.术后19例接受综合治疗,6例拒治,2例失访.术后6个月、1年、2年、3年生存率分别为92.6%、81.5%、51.9%、33.3%.结论 右膈肌侵犯不是肝癌切除禁忌证.合并右膈肌部分切除安全可行,而且远期疗效比较满意.
目的 探討肝癌閤併右膈肌部分切除的適應證、手術方法、術中應註意的問題,總結肝癌侵犯右膈肌的外科處理經驗.方法 對廣東省東莞市人民醫院1998年9月至2008年9月收治的27例肝癌閤併右膈肌部分切除患者的臨床資料進行迴顧性分析.結果 全部病例手術均穫得成功.切除腫瘤直徑5.0~15.0(平均8.5)cm,閤併切除右膈肌麵積9.0~50(平均28.5)cm2,手術時間110~250(平均165)min,失血量450~2600(平均870)ml.術後病理證實膈肌侵犯者9例(33.3%).術後全部病例均見少量右胸積液.其他併髮癥包括慢性肝功能不全4例及術後早期齣血、上消化道齣血、膽汁瘺、膈下感染各1例.所有患者經相應處理後均康複齣院,無圍手術期死亡病例.術後19例接受綜閤治療,6例拒治,2例失訪.術後6箇月、1年、2年、3年生存率分彆為92.6%、81.5%、51.9%、33.3%.結論 右膈肌侵犯不是肝癌切除禁忌證.閤併右膈肌部分切除安全可行,而且遠期療效比較滿意.
목적 탐토간암합병우격기부분절제적괄응증、수술방법、술중응주의적문제,총결간암침범우격기적외과처리경험.방법 대광동성동완시인민의원1998년9월지2008년9월수치적27례간암합병우격기부분절제환자적림상자료진행회고성분석.결과 전부병례수술균획득성공.절제종류직경5.0~15.0(평균8.5)cm,합병절제우격기면적9.0~50(평균28.5)cm2,수술시간110~250(평균165)min,실혈량450~2600(평균870)ml.술후병리증실격기침범자9례(33.3%).술후전부병례균견소량우흉적액.기타병발증포괄만성간공능불전4례급술후조기출혈、상소화도출혈、담즙루、격하감염각1례.소유환자경상응처리후균강복출원,무위수술기사망병례.술후19례접수종합치료,6례거치,2례실방.술후6개월、1년、2년、3년생존솔분별위92.6%、81.5%、51.9%、33.3%.결론 우격기침범불시간암절제금기증.합병우격기부분절제안전가행,이차원기료효비교만의.
Objective To review the indications,surgical methods,and matters which need attention in partial right diaphragmatic resection,and to summarize our experience of surgical therapy for hepatocellular carcinoma with right diaphragmatic invasion.Methods The clinical data of 27 patients with hepatocellular carcinoma which had invaded the diaphragm and had received partial right diaphragmatic resection and partial hepatectomy in our hospital from September 2008 to September 2012 were retrospectively analyzed.Results The operations were all performed successfully.The tumor diameter ranged from 5.0 to 15.0 cm (average 8.5 cm).The area of right diaphragm which was resected ranged from 9.0 to 50.0 cm2 (average 28.5 cm2).The operation time was 110~250 min (average 165 min),and blood loss was 450~2600 ml (average 870 ml).Diaphragmatic invasion was confirmed by postoperative histopathology in 9 patients (33.3%).A small quantity of right thoracic effusion was detected in all the cases postoperatively.Other complications included hepatic insufficiency in 4 patients and early postoperative bleeding,upper gastrointestinal bleeding,biliary fistula,and infection under the diaphragm in 1 case each.All patients recovered after conservative treatment.There was no perioperative death.19 patients received other postoperative adjuvant treatment while 6 patients refused further treatment and 2 patients were lost to follow-up.The 0.5-,1-,2,and 3 year survival rates after operation were 92.6%,81.5%,51.9% and 33.3% respectively.Conclusions Right diaphragmatic invasion is not a contraindication to surgery.Right diaphragmatic resection was safe and feasible,and postoperative long-term survival was satisfactory.