CAJ | 학술논문

医源性胆管损伤的发病率逐年升高.胆肠吻合等传统的治疗方法仍然存在严重并发症的重要原因之一就是废除了Oddi括约肌功能.随着组织工程及转化医学理念的发展,疾病的外科治疗越来越注重保留正常生理功能.该文综述了近年来保留Oddi括约肌或尽量恢复胆道功能结构的治疗策略,希望给临床相关研究提供参考.
의원성담관손상적발병솔축년승고.담장문합등전통적치료방법잉연존재엄중병발증적중요원인지일취시폐제료Oddi괄약기공능.수착조직공정급전화의학이념적발전,질병적외과치료월래월주중보류정상생리공능.해문종술료근년래보류Oddi괄약기혹진량회복담도공능결구적치료책략,희망급림상상관연구제공삼고.
In recent years,the incidence of iatrogenic bile duct injury has increased.The traditional treatment methods often cause severe complications,such as biliary-enteric anastomosis,which removes the sphincter of Oddi's function.With the development and potential translational use of engineered tissue,surgeons have focused on keeping normal physiological function after operations.In this manuscript,we review the strategy to repair bile duct defects without sacrificing the sphincter of Oddi' s function.This article may be referenced for clinical research.