中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2014年
5期
395-400
,共6页
徐后云%胡红杰%余细平%徐甜甜
徐後雲%鬍紅傑%餘細平%徐甜甜
서후운%호홍걸%여세평%서첨첨
肝脏肿瘤%缺血性胆管损伤%肝动脉化疗栓塞术%并发症
肝髒腫瘤%缺血性膽管損傷%肝動脈化療栓塞術%併髮癥
간장종류%결혈성담관손상%간동맥화료전새술%병발증
Liver neoplasms%Ischemic bile duct injury%Transcatheter arterial chemoembolization (TACE)%Complication
作为肝脏恶性肿瘤非手术治疗的常用方法,经导管肝动脉化疗栓塞术(TACE)的有效性及安全性已被大家认可.但在随后的运用过程中,也产生诸多并发症,如:上消化道出血、肝功能衰竭、肺栓塞、栓塞性胆囊炎等.胆管损伤作为其严重并发症之一亦有多篇报道.虽然对该并发症的发生机制、危险因素以及临床治疗目前仍存在较多问题,但查阅文献迄今未见这一并发症的相关文献综述.本文综合国内外文献,对目前存在的问题作一系统论述.
作為肝髒噁性腫瘤非手術治療的常用方法,經導管肝動脈化療栓塞術(TACE)的有效性及安全性已被大傢認可.但在隨後的運用過程中,也產生諸多併髮癥,如:上消化道齣血、肝功能衰竭、肺栓塞、栓塞性膽囊炎等.膽管損傷作為其嚴重併髮癥之一亦有多篇報道.雖然對該併髮癥的髮生機製、危險因素以及臨床治療目前仍存在較多問題,但查閱文獻迄今未見這一併髮癥的相關文獻綜述.本文綜閤國內外文獻,對目前存在的問題作一繫統論述.
작위간장악성종류비수술치료적상용방법,경도관간동맥화료전새술(TACE)적유효성급안전성이피대가인가.단재수후적운용과정중,야산생제다병발증,여:상소화도출혈、간공능쇠갈、폐전새、전새성담낭염등.담관손상작위기엄중병발증지일역유다편보도.수연대해병발증적발생궤제、위험인소이급림상치료목전잉존재교다문제,단사열문헌흘금미견저일병발증적상관문헌종술.본문종합국내외문헌,대목전존재적문제작일계통논술.
Transcatheter arterial chemoembolization (TACE) has been widely applied in palliative treatment of unresectable primary and metastatic liver cancer,and its efficiency and safety also have been widely acknowledged.However,there is a wide range of related complications,such as upper gastrointestinal hemorrhage,liver failure,pulmonary embolism,embolic cholecystitis and so on.As a serious complication of TACE,bile duct injury has been reported intermittently since the introduction of hepatic arterial embolization therapy.However,the exact pathogenesis,predisposing factors and clinical implications of the injuries remain to be clarified.As we find,by far there is no literature review about the bile duct injury after TACE for liver malignant tumors both at home and abroad.Thus the purpose of our study was to discuss such current issue of bile duct injury,and 26 articles have been included and analyzed.