中华肝脏病杂志
中華肝髒病雜誌
중화간장병잡지
CHINESE JOURNAL OF HEPATOLOGY
2014年
7期
536-539
,共4页
时淑云%韩军军%闫茗%王克菲%于红卫%孟庆华
時淑雲%韓軍軍%閆茗%王剋菲%于紅衛%孟慶華
시숙운%한군군%염명%왕극비%우홍위%맹경화
肝病,慢性%营养风险%NRS-2002
肝病,慢性%營養風險%NRS-2002
간병,만성%영양풍험%NRS-2002
Liver disease,chronic%Nutritional risk%NRS-2002
目的 应用欧洲营养风险筛查方法(NRS-2002)探讨不同程度肝病住院患者存在的营养风险,评估NRS-2002应用于肝病患者的可行性. 方法 对366例患者进行营养风险调查,符合NRS-2002评定标准者于入院当天进行营养风险评分,NRS-2002≥3分者判定为存在营养不良风险,以体质量指数(BMI)小于18.5 kg/m2,判定为营养不良;不符合NRS-2002评定标准的,于入院次日清晨留血检测血清白蛋白,白蛋白＜35 g/L者判定为营养不良.计数资料以相对数表示,组间比较采用x2检验. 结果 210例患者适用于NRS-2002,其总营养风险发生率为41.0％,营养不良总发生率为7.6％,其中以肝衰竭营养风险发生率最高(72.8％),97例肝硬化Child-Pugh A、B级患者营养风险发生率分别为33.1％、88.6％(x2=24.019,P=0.000),不同病因患者,其营养风险发生率以酒精性相关肝病最高(66.7％);不能应用NRS-2002的156例患者总营养不良发生率为76.2％. 结论 NRS-2002对肝病早期及轻症患者具有一定的适用性,但易出现假阳性,NRS-2002应用于终末期肝病患者存在局限性.
目的 應用歐洲營養風險篩查方法(NRS-2002)探討不同程度肝病住院患者存在的營養風險,評估NRS-2002應用于肝病患者的可行性. 方法 對366例患者進行營養風險調查,符閤NRS-2002評定標準者于入院噹天進行營養風險評分,NRS-2002≥3分者判定為存在營養不良風險,以體質量指數(BMI)小于18.5 kg/m2,判定為營養不良;不符閤NRS-2002評定標準的,于入院次日清晨留血檢測血清白蛋白,白蛋白＜35 g/L者判定為營養不良.計數資料以相對數錶示,組間比較採用x2檢驗. 結果 210例患者適用于NRS-2002,其總營養風險髮生率為41.0％,營養不良總髮生率為7.6％,其中以肝衰竭營養風險髮生率最高(72.8％),97例肝硬化Child-Pugh A、B級患者營養風險髮生率分彆為33.1％、88.6％(x2=24.019,P=0.000),不同病因患者,其營養風險髮生率以酒精性相關肝病最高(66.7％);不能應用NRS-2002的156例患者總營養不良髮生率為76.2％. 結論 NRS-2002對肝病早期及輕癥患者具有一定的適用性,但易齣現假暘性,NRS-2002應用于終末期肝病患者存在跼限性.
목적 응용구주영양풍험사사방법(NRS-2002)탐토불동정도간병주원환자존재적영양풍험,평고NRS-2002응용우간병환자적가행성. 방법 대366례환자진행영양풍험조사,부합NRS-2002평정표준자우입원당천진행영양풍험평분,NRS-2002≥3분자판정위존재영양불량풍험,이체질량지수(BMI)소우18.5 kg/m2,판정위영양불량;불부합NRS-2002평정표준적,우입원차일청신류혈검측혈청백단백,백단백＜35 g/L자판정위영양불량.계수자료이상대수표시,조간비교채용x2검험. 결과 210례환자괄용우NRS-2002,기총영양풍험발생솔위41.0％,영양불량총발생솔위7.6％,기중이간쇠갈영양풍험발생솔최고(72.8％),97례간경화Child-Pugh A、B급환자영양풍험발생솔분별위33.1％、88.6％(x2=24.019,P=0.000),불동병인환자,기영양풍험발생솔이주정성상관간병최고(66.7％);불능응용NRS-2002적156례환자총영양불량발생솔위76.2％. 결론 NRS-2002대간병조기급경증환자구유일정적괄용성,단역출현가양성,NRS-2002응용우종말기간병환자존재국한성.
Objective To use the European Nutritional Risk Screening (NRS)-2002 survey tool to investigate nutritional risk associated to different degrees of liver disease and to assess its ability to identify the nutritional risk of hospitalized patients with chronic liver disease.Methods A total of 366 hospitalized patients were assessed with the NRS-2002 on the day of admission.Patients who meet the criteria for malnourishment (NRS-2002 score of＞3 points (severely impaired nutritional status with body mass index (BMI) ＜ 18.5 kg/m2) were selected for further study to deteemine liver function.Patients were classified according to liver dysfunction-related features,including cirrhosis status,Child-Pugh classification,and underlying disease causes (e.g.alcohol,hepatitis virus infection).Chi square test was used in statistical analysis of inter-group difference.Results The incidence of patients surveyed who were at nutritional risk was 41.0％,and the incidence of malnutrition was 7.6％.The patients with liver failure showed the highest rate of nutritional risk (72.8％).Moreover,among the 97 patients with liver cirrhosis,significantly more had Child-Pugh grade B than grade A (88.6％ vs.33.1％;x2 =24.019,P =0.000).The cause of liver failure with the highest incidence of nutritional risk was alcohol-related liver disease (66.7％).The overall malnutrition rate among the total 156 patients classified by the NRS-2002 as being at nutritional risk was 76.2％.Conclusion The NRS-2002 is a suitable screening tool for use in Chinese patients with mild early liver disease,but it must be interpreted carefully as its findings alone may promote a false positive rate.The NRS-2002 is less accurate in patients with end-stage liver disease.
