中华航海医学与高气压医学杂志
中華航海醫學與高氣壓醫學雜誌
중화항해의학여고기압의학잡지
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
2014年
3期
160-162
,共3页
高压氧治疗%急性面神经炎%疗效
高壓氧治療%急性麵神經炎%療效
고압양치료%급성면신경염%료효
HBO treatment%Acute face neuritis%Therapeutic effect
目的 观察高压氧(hyperbaric oxygen,HBO)联合药物综合治疗急性面神经炎的疗效.方法 按照病例纳入标准,选择临床急性面神经炎患者116例.经患者知情同意,签署知情同意书,并经医院伦理委员会同意后,将116例患者分为对照组和HBO组,每组58例.(1)对照组:甲钴胺注射液500 μg肌肉注射,1次/d,连用3周.维生素B1注射液1 mg肌肉注射,1次/d连用3周.阿昔洛韦片400 mg口服,3次/d,加用3周.激素冲击治疗:地塞米松10 mg+ 5％葡萄糖注射液250 ml静滴,1次/d,10 d后逐步减量;全身支持治疗:低分子右旋糖酐500 ml+注射用辅酶A 50 U静滴,1次/d,连用3周.(2) HBO组:在对照组药物治疗基础上,加用HBO治疗.HBO治疗:采用0.25 MPa (2.5 ATA),升压20 min,稳压吸氧60 min(带面罩间歇吸氧),氧浓度为99.5％,减压30 min.1次/d,10d为1个疗程.以上方法均治疗3周后进行疗效评价.结果 2组急性面神经炎患者经过3周治疗后,面神经功能评分较治疗前均增加[对照组:治疗前(8.8±4.4)分、治疗后(21.3±5.5)分;HBO组:治疗前(8.7±4.5)分、治疗后(26.4±3.4)分],差异均有统计学意义(P＜0.01);HBO组在3周治疗后的评分明显高于对照组(P＜0.05).结论 HBO综合治疗急性面神经炎疗效明显.
目的 觀察高壓氧(hyperbaric oxygen,HBO)聯閤藥物綜閤治療急性麵神經炎的療效.方法 按照病例納入標準,選擇臨床急性麵神經炎患者116例.經患者知情同意,籤署知情同意書,併經醫院倫理委員會同意後,將116例患者分為對照組和HBO組,每組58例.(1)對照組:甲鈷胺註射液500 μg肌肉註射,1次/d,連用3週.維生素B1註射液1 mg肌肉註射,1次/d連用3週.阿昔洛韋片400 mg口服,3次/d,加用3週.激素遲擊治療:地塞米鬆10 mg+ 5％葡萄糖註射液250 ml靜滴,1次/d,10 d後逐步減量;全身支持治療:低分子右鏇糖酐500 ml+註射用輔酶A 50 U靜滴,1次/d,連用3週.(2) HBO組:在對照組藥物治療基礎上,加用HBO治療.HBO治療:採用0.25 MPa (2.5 ATA),升壓20 min,穩壓吸氧60 min(帶麵罩間歇吸氧),氧濃度為99.5％,減壓30 min.1次/d,10d為1箇療程.以上方法均治療3週後進行療效評價.結果 2組急性麵神經炎患者經過3週治療後,麵神經功能評分較治療前均增加[對照組:治療前(8.8±4.4)分、治療後(21.3±5.5)分;HBO組:治療前(8.7±4.5)分、治療後(26.4±3.4)分],差異均有統計學意義(P＜0.01);HBO組在3週治療後的評分明顯高于對照組(P＜0.05).結論 HBO綜閤治療急性麵神經炎療效明顯.
목적 관찰고압양(hyperbaric oxygen,HBO)연합약물종합치료급성면신경염적료효.방법 안조병례납입표준,선택림상급성면신경염환자116례.경환자지정동의,첨서지정동의서,병경의원윤리위원회동의후,장116례환자분위대조조화HBO조,매조58례.(1)대조조:갑고알주사액500 μg기육주사,1차/d,련용3주.유생소B1주사액1 mg기육주사,1차/d련용3주.아석락위편400 mg구복,3차/d,가용3주.격소충격치료:지새미송10 mg+ 5％포도당주사액250 ml정적,1차/d,10 d후축보감량;전신지지치료:저분자우선당항500 ml+주사용보매A 50 U정적,1차/d,련용3주.(2) HBO조:재대조조약물치료기출상,가용HBO치료.HBO치료:채용0.25 MPa (2.5 ATA),승압20 min,은압흡양60 min(대면조간헐흡양),양농도위99.5％,감압30 min.1차/d,10d위1개료정.이상방법균치료3주후진행료효평개.결과 2조급성면신경염환자경과3주치료후,면신경공능평분교치료전균증가[대조조:치료전(8.8±4.4)분、치료후(21.3±5.5)분;HBO조:치료전(8.7±4.5)분、치료후(26.4±3.4)분],차이균유통계학의의(P＜0.01);HBO조재3주치료후적평분명현고우대조조(P＜0.05).결론 HBO종합치료급성면신경염료효명현.
Objective To observe the effects of HBO combined with comprehensive drug treatment on 58 cases of acute face neuritis.Methods In accordance with the case selection criteria,116 case of acute face neuritis were chosen for the study.With the knowledge and consent of the patients and following the signing of the letter of agreement and with the agreement of the Hospital Ethic Committee,1 16 patients were divided into 2 groups:the experimental group and the control group,each consisting of 58 patients.The patients in the control group were only treated with regular drug treatment,while the patients in the experimental group were offered HBO treatment and regular drug treatment as well.They were all treated for a succession of 3 weeks and observation was made on the therapeutic results of both groups.Results After 3 weeks of treatment,facial nerve function scores for the patients of both groups all increased when compared with those before treatment,with statistical significance (P ＜ 0.01).Scores for the patients in the experimental group were significantly higher than those for the patients of the control group (P ＜ 0.05).Conclusions Comprehensive HBO treatment seemed to produce significant effects in the treatment of acute face neuritis.
