CAJ | 학술논문

目的探讨常压高流量氧治疗胎儿阵发性室上性心动过速(SVT)的疗效.方法选择经多普勒超声检查诊断为胎儿阵发性SVT孕妇共35例,采用常压高流量氧疗法进行治疗.孕妇在常压环境下戴面罩吸氧,供氧浓度为99.5％,氧流量为10 L/min,吸氧时间为30 min,中间间歇5 min吸空气,每日吸氧1次,10次为1个疗程.每治疗1个疗程复查心脏彩色多普勒超声及外周多普勒检测以评定疗效.结果 35例中18例治疗1个疗程、11例治疗2个疗程SVT消失,3例转为偶发性房性早搏,治疗总有效率91.4％,治愈率82.9％.治疗后胎儿心率、心胸面积比小于治疗前,心脏缩短分数、大脑中动脉搏动指数大于治疗前,差异均有统计学意义(P＜0.01).结论缺氧可能是诱发胎儿阵发性室上性心动过速的因素之一,常压高流量氧可有效抑制胎儿阵发性SVT,疗效肯定,无创,安全.
목적 탐토상압고류량양치료태인진발성실상성심동과속(SVT)적료효.방법 선택경다보륵초성검사진단위태인진발성SVT잉부공35례,채용상압고류량양요법진행치료.잉부재상압배경하대면조흡양,공양농도위99.5％,양류량위10 L/min,흡양시간위30 min,중간간헐5 min흡공기,매일흡양1차,10차위1개료정.매치료1개료정복사심장채색다보륵초성급외주다보륵검측이평정료효.결과 35례중18례치료1개료정、11례치료2개료정SVT소실,3례전위우발성방성조박,치료총유효솔91.4％,치유솔82.9％.치료후태인심솔、심흉면적비소우치료전,심장축단분수、대뇌중동맥박동지수대우치료전,차이균유통계학의의(P＜0.01).결론 결양가능시유발태인진발성실상성심동과속적인소지일,상압고류량양가유효억제태인진발성SVT,료효긍정,무창,안전.
Objective To explore the effect of high-flow oxygen inhalation outside the chamber on fetal paroxysmal supraventricular tachycardia (SVT).Methods Thirty-five cases of fetal paroxysmal SVT that were diagnosed by fetal Doppler altrasonography were treated with high-flow oxygen inhalation outside the chamber.The pregnant women inhaled 99.5％ oxygen with breathing masks at a flow rate of 10 liters/min.Oxygen breathing time was 30 minutes,with an interval of 5 minutes.They were treated one session a day,with 10 sessions being a treatment course.Fetal cardiac and peripheral color Doppler altrasonography was performed at the end of each treatment course to evaluate the therapeutic effects.Results Of the 35 cases,18 cases did not have SVT any longer after 1 course of treatment,11 cases were without SVT any more after 2 courses of treatment,and 3 cases turned to have occasional atrial premature beat,with a total effective rate of 91.4％ and cure rate of 82.9％.Fetal heart rate and heart/chest ratio after treatment were significantly lower than those before treatment.Cardiac fractional index and pulsation index of middle cerebral artery were significantly higher than those before treatment,with statistical significance (P ＜ 0.Ol).Conclusions Hypoxia is possibly one of the causes that induce fetal SVT.High-flow oxygen inhalation outside the chamber is a positive,noninvasive and safe treatment method that could effectively inhibit fetal paroxysmal SVT.