中华核医学与分子影像杂志
中華覈醫學與分子影像雜誌
중화핵의학여분자영상잡지
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014年
3期
253-256
,共4页
肌萎缩侧索硬化%体层摄影术,发射型计算机,单光子%体层摄影术,发射型计算机%发展趋势
肌萎縮側索硬化%體層攝影術,髮射型計算機,單光子%體層攝影術,髮射型計算機%髮展趨勢
기위축측색경화%체층섭영술,발사형계산궤,단광자%체층섭영술,발사형계산궤%발전추세
Amyotrophic lateral sclerosis%Tomography,emission-computed,single-photon%Tomography,emission-computed%Trends
肌萎缩侧索硬化(ALS)起病隐匿、进展迅速、诊断困难,其神经影像学改变目前尚缺乏明确特异性指征.SPECT和PET是最早应用于ALS的神经影像学技术.像素分析软件的运用(如SPM等)使SPECT、PET对ALS的研究更加方便和客观.近年来,脑受体PET显像不断发展,逐渐显示出其在ALS早期诊断及认知功能受损研究中的重要价值.
肌萎縮側索硬化(ALS)起病隱匿、進展迅速、診斷睏難,其神經影像學改變目前尚缺乏明確特異性指徵.SPECT和PET是最早應用于ALS的神經影像學技術.像素分析軟件的運用(如SPM等)使SPECT、PET對ALS的研究更加方便和客觀.近年來,腦受體PET顯像不斷髮展,逐漸顯示齣其在ALS早期診斷及認知功能受損研究中的重要價值.
기위축측색경화(ALS)기병은닉、진전신속、진단곤난,기신경영상학개변목전상결핍명학특이성지정.SPECT화PET시최조응용우ALS적신경영상학기술.상소분석연건적운용(여SPM등)사SPECT、PET대ALS적연구경가방편화객관.근년래,뇌수체PET현상불단발전,축점현시출기재ALS조기진단급인지공능수손연구중적중요개치.
Amyotrophic lateral sclerosis (ALS),a neurodegenerative disorder,is subtle in disease onset,difficult to diagnose,and fast-growing at progression.There.are at present little specific neurological imaging characteristics of ALS.Functional brain imaging techniques,such as SPECT and PET,were the early tools for investigation of ALS.The application of pixel-based analysis software (such as SPM) renders research in this area more convenient and objective.In recent years,improvement in brain receptor PET imaging has demonstrated its important value in the early diagnosis of ALS and evaluation of cognitive impairment.
