CAJ | 학술논문

CD133作为一种干细胞表面标志物,已被证实在多种肿瘤中表达.甲状腺癌干细胞的特异性标志物还未明确.研究报道已经发现在未分化型甲状腺癌细胞中有CD133表达,且这类细胞具有干细胞的特点,能够自我更新、多向分化和有发展成癌的潜力,也具有抵抗放化疗的作用.笔者针对CD133在甲状腺癌中的研究进展作一综述.
CD133작위일충간세포표면표지물,이피증실재다충종류중표체.갑상선암간세포적특이성표지물환미명학.연구보도이경발현재미분화형갑상선암세포중유CD133표체,차저류세포구유간세포적특점,능구자아경신、다향분화화유발전성암적잠력,야구유저항방화료적작용.필자침대CD133재갑상선암중적연구진전작일종술.
CD133 has been confirmed as a stem cell surface marker in a variety of tumors.Specific markers of cancer stem cells in the thyroid cancer are not yet clear.Results of some studies showed that expression of CD133 was found in undifferentiated thyroid cancer cells which had the characteristics of stem cells.Those cells had the ability to self-renewal,multi-directional differentiation,potential development to cancer,and radio-and chemotherapy resistance.This article mainly views the progresses of CD133 in thyroid cancer research.