中华精神科杂志
中華精神科雜誌
중화정신과잡지
CHINESE JOURNA OF PSYCHIATRY
2013年
3期
164-168
,共5页
李菁晶%袁怀武%张宁%石玉芝%白莹%周永%周娟%于欣%孙新宇
李菁晶%袁懷武%張寧%石玉芝%白瑩%週永%週娟%于訢%孫新宇
리정정%원부무%장저%석옥지%백형%주영%주연%우흔%손신우
脑血管意外%抑郁%复发%前瞻性研究%队列研究
腦血管意外%抑鬱%複髮%前瞻性研究%隊列研究
뇌혈관의외%억욱%복발%전첨성연구%대렬연구
Cerebrovascular accident%Depression%Recurrence%Prospective studies%Cohort studies
目的 探讨缺血性卒中患者急性期发生的卒中后抑郁障碍(poststroke depression,PSD)与1年卒中复发风险的相关性.方法 根据《美国精神障碍诊断与统计手册(第4版)》抑郁障碍诊断标准,对1897例连续入组的急性缺血性卒中住院患者,在卒中后2周进行抑郁障碍的诊断;利用logistic回归分析计算PSD患者的1年卒中复发OR值及95%可信区间(CI).结果 共1460例患者的随访数据完整,其中390例(26.7%)患者在卒中后2周符合PSD诊断,一年累计卒中复发153例(10.5%).多变量logistic回归分析显示,与非PSD患者比较,PSD患者的1年卒中复发风险增加48%(OR=1.48;95% CI:1.01 ~2.15;P<0.05).结论 缺血性卒中患者急性期发生的PSD可能增加1年卒中复发风险.
目的 探討缺血性卒中患者急性期髮生的卒中後抑鬱障礙(poststroke depression,PSD)與1年卒中複髮風險的相關性.方法 根據《美國精神障礙診斷與統計手冊(第4版)》抑鬱障礙診斷標準,對1897例連續入組的急性缺血性卒中住院患者,在卒中後2週進行抑鬱障礙的診斷;利用logistic迴歸分析計算PSD患者的1年卒中複髮OR值及95%可信區間(CI).結果 共1460例患者的隨訪數據完整,其中390例(26.7%)患者在卒中後2週符閤PSD診斷,一年纍計卒中複髮153例(10.5%).多變量logistic迴歸分析顯示,與非PSD患者比較,PSD患者的1年卒中複髮風險增加48%(OR=1.48;95% CI:1.01 ~2.15;P<0.05).結論 缺血性卒中患者急性期髮生的PSD可能增加1年卒中複髮風險.
목적 탐토결혈성졸중환자급성기발생적졸중후억욱장애(poststroke depression,PSD)여1년졸중복발풍험적상관성.방법 근거《미국정신장애진단여통계수책(제4판)》억욱장애진단표준,대1897례련속입조적급성결혈성졸중주원환자,재졸중후2주진행억욱장애적진단;이용logistic회귀분석계산PSD환자적1년졸중복발OR치급95%가신구간(CI).결과 공1460례환자적수방수거완정,기중390례(26.7%)환자재졸중후2주부합PSD진단,일년루계졸중복발153례(10.5%).다변량logistic회귀분석현시,여비PSD환자비교,PSD환자적1년졸중복발풍험증가48%(OR=1.48;95% CI:1.01 ~2.15;P<0.05).결론 결혈성졸중환자급성기발생적PSD가능증가1년졸중복발풍험.
Objective To investigate whether depression in acute phase of ischemic stroke could increase risk of recurrent stroke at 1 year.Methods This was a multi-centered prospective cohort study.1897 patients with acute ischemic stroke were enrolled consecutively.The Diagnostic and Statistical Manual of Mental Disorders,fourth edition (DSM-Ⅳ) was used as criteria for diagnosis of depression.Results In 1460 patients who complete follow-up data,967 (66.2%) were male with a mean of 61.1 years of age,and 493 (33.8%) were female with mean of 64.5 years of age.There were 390 (26.7%) cases of depression at 2 weeks,and 153 (10.5%) cases of cumulative recurrent stroke at 1 year.Multivariate logistic regression analysis showed a 48% increase of risk of recurrent stroke at 1 year in patients with depression compared to patients without depression (OR =1.48,95% CI:1.01-2.15,P < 0.05).Conclusions Depression in acute phase of ischemic stroke is possibly related with a higher risk of recurrent stroke at 1 year.