CAJ | 학술논문

目的探讨国际标准化比值(international normalized ratio,INR) ＜2.5、拔牙术前不停服抗凝剂华法林的可行性.方法选取门诊100例拔牙术前不停服华法林且INR值＜2.5的60岁以上拔牙患者为观察组,200例拔牙术前未服抗凝及抗血小板药物的60岁以上拔牙患者为对照组,均拔除单颗非阻生牙,观察拔牙术后不同时间段的出血情况.结果两组患者拔牙术后5、10、30 min、24h 出血发生率差异有统计学意义(P＜0.05),48 h两组均无出血发生(出血发生率为0％).结论经规范的拔牙操作同时有术后积极的出血监控和相应的止血处理措施,老年人拔除单颗非阻生牙术前INR值＜2.5不停服华法林是可行的.
목적 탐토국제표준화비치(international normalized ratio,INR) ＜2.5、발아술전불정복항응제화법림적가행성.방법 선취문진100례발아술전불정복화법림차INR치＜2.5적60세이상발아환자위관찰조,200례발아술전미복항응급항혈소판약물적60세이상발아환자위대조조,균발제단과비조생아,관찰발아술후불동시간단적출혈정황.결과 량조환자발아술후5、10、30 min、24h 출혈발생솔차이유통계학의의(P＜0.05),48 h량조균무출혈발생(출혈발생솔위0％).결론 경규범적발아조작동시유술후적겁적출혈감공화상응적지혈처리조시,노년인발제단과비조생아술전INR치＜2.5불정복화법림시가행적.
Objective To investigate the feasibility of continuing warfarin when international normalized ratio (INR) was less than 2.5 before tooth extraction in the elderly.Methods One hundred elderly outpatients with prolong use of warfarin and maintaining INR ＜ 2.5 before tooth extraction served as observation group,200 elderly outpatients without taking anticoagulant and antiplatelet medicine served as control group.All the patients underwent a single non-impacted tooth extraction.Postoperative bleeding at different time was observed.Results There was significant difference in postoperative bleeding at 5,10,30 min,24 h after extraction and there was no significant difference at 48 h between control group and observation group(P ＜0.05)and no bleeding was found in either group at 48 h(incidence of bleeding were 0％).Conclusions It was feasible to continue warfarin for the elderly maintaining INR ＜ 2.5 undergoing a single non-impacted tooth extraction by monitoring postoperative bleeding and hemostatic treatment measures.