中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2013年
8期
494-498
,共5页
赵岩%淺里仁%高平%井上美津子
趙巖%淺裏仁%高平%井上美津子
조암%천리인%고평%정상미진자
牙髓复盖术%三维,成像%微焦点CT%三氧化矿物凝聚体
牙髓複蓋術%三維,成像%微焦點CT%三氧化礦物凝聚體
아수복개술%삼유,성상%미초점CT%삼양화광물응취체
Dental pulp capping%Imaging,three-dimensional%Micro-CT%Mineral triozide aggregate
目的 定量研究三氧化矿物凝聚体(mineral triozide aggregate,MTA)和氢氧化钙糊剂(Vitapex)用于鼠牙直接盖髓后的牙根体积变化,以期为盖髓剂的临床应用提供参考.方法 选取1个月龄雌性Wistar大鼠64只,用随机数字表法均分为4组:MTA组、氢氧化钙组、模型对照组和空白对照组,每组16只.人工机械暴露大鼠右侧上颌第一磨牙牙髓,实验组分别用MTA和氢氧化钙糊剂Vitapex直接盖髓,模型对照组采用无菌生理盐水棉球盖髓,空白对照组不做任何处理.应用微型CT和三维重建技术,观察各组术后1、2、4及6周牙根体积的变化,并进行单因素方差分析和LSD-t检验,检验水准为双侧α =0.05.结果 术后2、4周,MTA组的牙根体积[(1.08±0.07)、(1.32±0.18)mm3]均显著小于氢氧化钙组[(1.28 ±0.16)、(1.59±0.18) mm3],差异均有统计学意义(P＜0.05)；术后6周MTA组的牙根体积[(1.36 ±0.03) mm3]与氢氧化钙组[(1.61±0.31) mm3]差异无统计学意义(P＞0.05)；术后2、4、6周,MTA组和氢氧化钙组的牙根体积均显著大于模型对照组[(0.87±0.09)、(1.01±0.17)、(1.02±0.25) mm3],差异均有统计学意义(P＜0.05).结论 MTA和氢氧化钙糊剂均可促进牙根继续发育形成,是具有良好生物活性的盖髓剂.
目的 定量研究三氧化礦物凝聚體(mineral triozide aggregate,MTA)和氫氧化鈣糊劑(Vitapex)用于鼠牙直接蓋髓後的牙根體積變化,以期為蓋髓劑的臨床應用提供參攷.方法 選取1箇月齡雌性Wistar大鼠64隻,用隨機數字錶法均分為4組:MTA組、氫氧化鈣組、模型對照組和空白對照組,每組16隻.人工機械暴露大鼠右側上頜第一磨牙牙髓,實驗組分彆用MTA和氫氧化鈣糊劑Vitapex直接蓋髓,模型對照組採用無菌生理鹽水棉毬蓋髓,空白對照組不做任何處理.應用微型CT和三維重建技術,觀察各組術後1、2、4及6週牙根體積的變化,併進行單因素方差分析和LSD-t檢驗,檢驗水準為雙側α =0.05.結果 術後2、4週,MTA組的牙根體積[(1.08±0.07)、(1.32±0.18)mm3]均顯著小于氫氧化鈣組[(1.28 ±0.16)、(1.59±0.18) mm3],差異均有統計學意義(P＜0.05)；術後6週MTA組的牙根體積[(1.36 ±0.03) mm3]與氫氧化鈣組[(1.61±0.31) mm3]差異無統計學意義(P＞0.05)；術後2、4、6週,MTA組和氫氧化鈣組的牙根體積均顯著大于模型對照組[(0.87±0.09)、(1.01±0.17)、(1.02±0.25) mm3],差異均有統計學意義(P＜0.05).結論 MTA和氫氧化鈣糊劑均可促進牙根繼續髮育形成,是具有良好生物活性的蓋髓劑.
목적 정량연구삼양화광물응취체(mineral triozide aggregate,MTA)화경양화개호제(Vitapex)용우서아직접개수후적아근체적변화,이기위개수제적림상응용제공삼고.방법 선취1개월령자성Wistar대서64지,용수궤수자표법균분위4조:MTA조、경양화개조、모형대조조화공백대조조,매조16지.인공궤계폭로대서우측상합제일마아아수,실험조분별용MTA화경양화개호제Vitapex직접개수,모형대조조채용무균생리염수면구개수,공백대조조불주임하처리.응용미형CT화삼유중건기술,관찰각조술후1、2、4급6주아근체적적변화,병진행단인소방차분석화LSD-t검험,검험수준위쌍측α =0.05.결과 술후2、4주,MTA조적아근체적[(1.08±0.07)、(1.32±0.18)mm3]균현저소우경양화개조[(1.28 ±0.16)、(1.59±0.18) mm3],차이균유통계학의의(P＜0.05)；술후6주MTA조적아근체적[(1.36 ±0.03) mm3]여경양화개조[(1.61±0.31) mm3]차이무통계학의의(P＞0.05)；술후2、4、6주,MTA조화경양화개조적아근체적균현저대우모형대조조[(0.87±0.09)、(1.01±0.17)、(1.02±0.25) mm3],차이균유통계학의의(P＜0.05).결론 MTA화경양화개호제균가촉진아근계속발육형성,시구유량호생물활성적개수제.
Objective To evaluate the volume change of rat root following direct pulp capping with mineral triozide aggregate (MTA) and calcium hydroxide-based paste (Vitapex).Methods Sixty-four female,1-month-old Wistar rats were randomly divided into 4 groups,MTA group,Vitapex group,model group and control group,16 rats in each group.The right maxillary first molar was taken as experimental tooth and control tooth.The exposed pulp was capped separately with MTA and calcium hydroxide after the pulp had been exposed mechanically,while nothing done to the control group.Using micro-CT and three-dimensional reconstruction techniques,the volume change of rat root was evaluated at 1,2,4 weeks and 6 weeks after direct pulp capping.The data were analyzed by an way ANOVA analysis followed by a LSD-t test.Results The root volume in the MTA group [(1.08 ± 0.07),(1.32 ± 0.18) mm3] was significantly smaller than that in the Vitapex group[(1.28 ±0.16),(1.59 ±0.18) mm3] at 2 and 4 weeks after operation(P ＜0.05).At the sixth week,there was no significant difference between the MTA group [(1.36 ± 0.03) mm3] and the Vitapex group [(1.61 ± 0.31) mm3] (P ＞ 0.05).The root volume in the MTA group and Vitapex group was significantly larger than that in the model group [(0.87 ± 0.09),(1.01±0.17),(1.02 ± 0.25) mm3] from the second to sixth week after operation(P ＜ 0.05).Conclusions MTA and Vitapex can effectively promote root formation and growth and can be used as biological pulp-capping material.
