中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2013年
z1期
53-57
,共5页
林仪%林韩%朱萍%许跃%郑有华
林儀%林韓%硃萍%許躍%鄭有華
림의%림한%주평%허약%정유화
腮腺炎%涎腺导管%唾液%计算流体动力学
腮腺炎%涎腺導管%唾液%計算流體動力學
시선염%연선도관%타액%계산류체동역학
Parotitis%Salivary ducts%Saliva%Computational fluid dynamics
目的 研究腮腺导管阻塞物体积对导管内唾液流场特征的影响,以期为阻塞性腮腺疾病的发病机制提供理论依据.方法 利用正常腮腺造影CT扫描资料建立腮腺导管系统数值模型,利用Mimics软件及Gambit软件提取腮腺导管立体轮廓并进行三维网格划分,应用Fluent软件进行导管内唾液流体动力学分析.结果 腮腺导管阻塞物上游流体压力(6.40～19.82 Pa)显著高于下游压力(2.78 Pa) (P ＜0.05),压力随阻塞率增大而升高.阻塞率为60％是导管内流体压力升高的突变点；导管阻塞率＞90％时患者即出现局部胀痛症状.结论 腮腺导管阻塞率变化引起了导管内唾液压力的波动并出现相应临床症状.导管内唾液流体力学分析方法为涎腺阻塞性疾病的发病机制研究提供理论基础.
目的 研究腮腺導管阻塞物體積對導管內唾液流場特徵的影響,以期為阻塞性腮腺疾病的髮病機製提供理論依據.方法 利用正常腮腺造影CT掃描資料建立腮腺導管繫統數值模型,利用Mimics軟件及Gambit軟件提取腮腺導管立體輪廓併進行三維網格劃分,應用Fluent軟件進行導管內唾液流體動力學分析.結果 腮腺導管阻塞物上遊流體壓力(6.40～19.82 Pa)顯著高于下遊壓力(2.78 Pa) (P ＜0.05),壓力隨阻塞率增大而升高.阻塞率為60％是導管內流體壓力升高的突變點；導管阻塞率＞90％時患者即齣現跼部脹痛癥狀.結論 腮腺導管阻塞率變化引起瞭導管內唾液壓力的波動併齣現相應臨床癥狀.導管內唾液流體力學分析方法為涎腺阻塞性疾病的髮病機製研究提供理論基礎.
목적 연구시선도관조새물체적대도관내타액류장특정적영향,이기위조새성시선질병적발병궤제제공이론의거.방법 이용정상시선조영CT소묘자료건립시선도관계통수치모형,이용Mimics연건급Gambit연건제취시선도관입체륜곽병진행삼유망격화분,응용Fluent연건진행도관내타액류체동역학분석.결과 시선도관조새물상유류체압력(6.40～19.82 Pa)현저고우하유압력(2.78 Pa) (P ＜0.05),압력수조새솔증대이승고.조새솔위60％시도관내류체압력승고적돌변점；도관조새솔＞90％시환자즉출현국부창통증상.결론 시선도관조새솔변화인기료도관내타액압력적파동병출현상응림상증상.도관내타액류체역학분석방법위연선조새성질병적발병궤제연구제공이론기출.
Objective To further understand the pathophysiological mechanism for obstructive parotid diseases by investigating the effect of maximal sialolith blockage ratio to the characteristics of saliva flow field in the Stensen's duct.Methods The epidemiologic and clinical data of 16 patients with chronic obstructive parotitis were retrospectively analyzed.Numerical model of Stensen's duct was reconstructed by Mimics 14.11 after CT sialography of the volunteer and the calculation models of obstruction were meshed by Gambit 2.1.30.Then the finite volume techniques based on Fluent 6.1 were employed to analyze the fluid dynamics of saliva around various sizes of sialolith.Finally,the change rule of intraductal pressure and its turning point were illuminated.Results The upstream pressure ranging from 6.40 Pa to 19.82 Pa was higher than that of downstream pressure (2.78 Pa) in the same blockage ratio (P ＜ 0.05),and increased as the blockage ratio increased.Statistically,the pressure turning point was indicated when blockage ratio was equal to 60％.Only when the blockage ratio was greater than 90％ did the patients feel the painful swelling under the stimulated condition.Conclusions The obstructive symptoms causing regular pressure fluctuation in Stensen's duct are associated with the blockage ratio changes of obstruction in clinical.Construction of simulation model and analysis of salivary fluid dynamics with CT sialography in Stensen's duct may provide a further pathophysiological mechanism for obstructive diseases.
