中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2014年
4期
199-203
,共5页
刘怡杰%荣文笙%赵秀兰%王萌%姜全春%王伟健
劉怡傑%榮文笙%趙秀蘭%王萌%薑全春%王偉健
류이걸%영문생%조수란%왕맹%강전춘%왕위건
龋齿%窝沟封闭剂%第一恒磨牙%防龋效果
齲齒%窩溝封閉劑%第一恆磨牙%防齲效果
우치%와구봉폐제%제일항마아%방우효과
Dental caries%Pit and fissure sealants%The first permanent molars%Caries prevention effect
目的 观察树脂型和玻璃离子型两种窝沟封闭剂对第一恒磨牙的防龋效果,以期为儿童龋病预防工作提供依据.方法 采用随机、空白对照、受试者单盲、为期2年的研究设计,选取至少有1颗第一恒磨牙有深窝沟或非成洞龋的7~9岁儿童419人(共计664颗第一恒磨牙)为研究对象,采用分层随机的方法将入选儿童分为3组,R组(136人,219颗牙)使用光固化树脂型封闭剂(Helioseal F)封闭;G组(130人,218颗牙)使用光固化玻璃离子型封闭剂(FUJIⅦ)封闭;N组(153人,227颗牙)为空白对照组.在封闭后6、12及24个月时回访,观察3组儿童第一恒磨牙新生龋的发病情况,采用卡方检验分析3组间龋病发病率的差异,使用广义估计方程分析不同干预方式、纳入研究的牙位分布及封闭前窝沟状况对龋病发病率的影响.结果 R组2年龋病发病率为3.0%(6/197),G组为6.7%(13/193),N组为14.7%(29/197),3组间差异有统计学意义(P<0.05),R组和G组间差异无统计学意义(P>0.05).2年回访时与N组相比,使用树脂型封闭剂预防了79.6%的龋齿,使用玻璃离子型封闭剂预防了54.4%的龋齿.结论 树脂型封闭剂和玻璃离子型封闭剂均能有效预防第一恒磨牙龋病的发生,两种材料的防龋效果相似.
目的 觀察樹脂型和玻璃離子型兩種窩溝封閉劑對第一恆磨牙的防齲效果,以期為兒童齲病預防工作提供依據.方法 採用隨機、空白對照、受試者單盲、為期2年的研究設計,選取至少有1顆第一恆磨牙有深窩溝或非成洞齲的7~9歲兒童419人(共計664顆第一恆磨牙)為研究對象,採用分層隨機的方法將入選兒童分為3組,R組(136人,219顆牙)使用光固化樹脂型封閉劑(Helioseal F)封閉;G組(130人,218顆牙)使用光固化玻璃離子型封閉劑(FUJIⅦ)封閉;N組(153人,227顆牙)為空白對照組.在封閉後6、12及24箇月時迴訪,觀察3組兒童第一恆磨牙新生齲的髮病情況,採用卡方檢驗分析3組間齲病髮病率的差異,使用廣義估計方程分析不同榦預方式、納入研究的牙位分佈及封閉前窩溝狀況對齲病髮病率的影響.結果 R組2年齲病髮病率為3.0%(6/197),G組為6.7%(13/193),N組為14.7%(29/197),3組間差異有統計學意義(P<0.05),R組和G組間差異無統計學意義(P>0.05).2年迴訪時與N組相比,使用樹脂型封閉劑預防瞭79.6%的齲齒,使用玻璃離子型封閉劑預防瞭54.4%的齲齒.結論 樹脂型封閉劑和玻璃離子型封閉劑均能有效預防第一恆磨牙齲病的髮生,兩種材料的防齲效果相似.
목적 관찰수지형화파리리자형량충와구봉폐제대제일항마아적방우효과,이기위인동우병예방공작제공의거.방법 채용수궤、공백대조、수시자단맹、위기2년적연구설계,선취지소유1과제일항마아유심와구혹비성동우적7~9세인동419인(공계664과제일항마아)위연구대상,채용분층수궤적방법장입선인동분위3조,R조(136인,219과아)사용광고화수지형봉폐제(Helioseal F)봉폐;G조(130인,218과아)사용광고화파리리자형봉폐제(FUJIⅦ)봉폐;N조(153인,227과아)위공백대조조.재봉폐후6、12급24개월시회방,관찰3조인동제일항마아신생우적발병정황,채용잡방검험분석3조간우병발병솔적차이,사용엄의고계방정분석불동간예방식、납입연구적아위분포급봉폐전와구상황대우병발병솔적영향.결과 R조2년우병발병솔위3.0%(6/197),G조위6.7%(13/193),N조위14.7%(29/197),3조간차이유통계학의의(P<0.05),R조화G조간차이무통계학의의(P>0.05).2년회방시여N조상비,사용수지형봉폐제예방료79.6%적우치,사용파리리자형봉폐제예방료54.4%적우치.결론 수지형봉폐제화파리리자형봉폐제균능유효예방제일항마아우병적발생,량충재료적방우효과상사.
Objective To evaluate the effectiveness of resin-based sealants and glass ionomer sealants on caries prevention in the first permanent molars.Methods A randomized controlled,examiner-blinded,2-year clinical trial with parallel groups was conducted.A total of 419 children(664 first molars) who had at least one sound first permanent molar with deep fissures or fissures with signs of non-cavitated lesions were recruited.They were randomly allocated into three groups.Helioseal F,a light-cured resin-based sealants was used in group R (136 children with 219 first molars).FUJI Ⅶ,a light-cured glass ionomer sealants was used in group G(130 children with 218 first molars) and group N (153 children with 227 first molars) was blank control.Follow-up examinations were conducted at 6,12,and 24 month after sealing to examine the sealants retention and caries incidence.Chi-square test was used to compare the differences of caries incidence among the 3 groups.Generalized estimating equations (GEE) was used to analyze the effective factors of caries incidence.Results During the 2-year follow-up period,3.0%(6/197) of the teeth in group R,6.7% (13/193) of the teeth in group G,and 14.7% (29/197) of the teeth in group N were diagnosed as having developed a cavitated lesion.The difference in the incidence of caries among the three groups was significant (P < 0.05).No significant difference in caries incidence was found between group R and group G (P > 0.05).The tooth-level preventive fractions were 79.6% for resin-based sealants and 54.4% for glass ionomer sealants,respectively.Conclusions Both resin-based sealants and glass ionomer sealants can effectively prevent the incidence of caries in the first permanent molars.The two sealants have similar caries prevention effect