中华临床感染病杂志
中華臨床感染病雜誌
중화림상감염병잡지
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
2012年
5期
270-273
,共4页
王万海%王庆芳%李建丽%王梅芬%刘家田%梅园丁%秦东春%明亮
王萬海%王慶芳%李建麗%王梅芬%劉傢田%梅園丁%秦東春%明亮
왕만해%왕경방%리건려%왕매분%류가전%매완정%진동춘%명량
感染%弓形虫属%风疹病毒%巨细胞病毒%单纯疱疹病毒属%育龄人群%流行病学
感染%弓形蟲屬%風疹病毒%巨細胞病毒%單純皰疹病毒屬%育齡人群%流行病學
감염%궁형충속%풍진병독%거세포병독%단순포진병독속%육령인군%류행병학
Infection%Toxoplasma%Rubella virus%Cytomegalovirus%Simplexvirus%People of childbearing age%Epidemiology
目的 了解目前河南省育龄人群感染弓形虫(Tox)、风疹病毒(RV)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)Ⅰ/Ⅱ型的现状.方法 采用酶联免疫吸附试验(ELISA)对2011年7-9月来郑州大学第一附属医院进行孕前咨询的3084例育龄男女进行上述病原(TORCH)感染的特异性IgM及IgG抗体检测.依据研究人群的性别及年龄进行分组,并对组间的TORCH特异性抗体阳性率采用x2检验进行统计学分析.结果 育龄人群TORCH IgM抗体总阳性率为5.5％ (170/3084),其中RV IgM抗体阳性率最高(2.9％),其次为HSV(1.0％)；在IgG抗体方面,HSV IgG抗体阳性率最高(90.4％),其次为CMV IgG(89.7％)、RV IgG(48.1％)和Tox IgG(0.7％).从年龄来看,＞ 30 ～ 40岁组各病原体的IgM抗体阳性率普遍较低；而IgG抗体方面,Tox、CMV及HSV IgG抗体阳性率随着年龄的增长呈现上升趋势,但RV IgG抗体阳性率却随着年龄的增长呈下降趋势.育龄女性人群的CMV和HSV IgG抗体阳性率显著高于男性(x2=83.470和7.026,P＜0.01).结论 河南省育龄人群中存在一定比例的TORCH现症感染及较低的RV IgG阳性率,建议育龄人群孕前进行TORCH筛查.
目的 瞭解目前河南省育齡人群感染弓形蟲(Tox)、風疹病毒(RV)、巨細胞病毒(CMV)、單純皰疹病毒(HSV)Ⅰ/Ⅱ型的現狀.方法 採用酶聯免疫吸附試驗(ELISA)對2011年7-9月來鄭州大學第一附屬醫院進行孕前咨詢的3084例育齡男女進行上述病原(TORCH)感染的特異性IgM及IgG抗體檢測.依據研究人群的性彆及年齡進行分組,併對組間的TORCH特異性抗體暘性率採用x2檢驗進行統計學分析.結果 育齡人群TORCH IgM抗體總暘性率為5.5％ (170/3084),其中RV IgM抗體暘性率最高(2.9％),其次為HSV(1.0％)；在IgG抗體方麵,HSV IgG抗體暘性率最高(90.4％),其次為CMV IgG(89.7％)、RV IgG(48.1％)和Tox IgG(0.7％).從年齡來看,＞ 30 ～ 40歲組各病原體的IgM抗體暘性率普遍較低；而IgG抗體方麵,Tox、CMV及HSV IgG抗體暘性率隨著年齡的增長呈現上升趨勢,但RV IgG抗體暘性率卻隨著年齡的增長呈下降趨勢.育齡女性人群的CMV和HSV IgG抗體暘性率顯著高于男性(x2=83.470和7.026,P＜0.01).結論 河南省育齡人群中存在一定比例的TORCH現癥感染及較低的RV IgG暘性率,建議育齡人群孕前進行TORCH篩查.
목적 료해목전하남성육령인군감염궁형충(Tox)、풍진병독(RV)、거세포병독(CMV)、단순포진병독(HSV)Ⅰ/Ⅱ형적현상.방법 채용매련면역흡부시험(ELISA)대2011년7-9월래정주대학제일부속의원진행잉전자순적3084례육령남녀진행상술병원(TORCH)감염적특이성IgM급IgG항체검측.의거연구인군적성별급년령진행분조,병대조간적TORCH특이성항체양성솔채용x2검험진행통계학분석.결과 육령인군TORCH IgM항체총양성솔위5.5％ (170/3084),기중RV IgM항체양성솔최고(2.9％),기차위HSV(1.0％)；재IgG항체방면,HSV IgG항체양성솔최고(90.4％),기차위CMV IgG(89.7％)、RV IgG(48.1％)화Tox IgG(0.7％).종년령래간,＞ 30 ～ 40세조각병원체적IgM항체양성솔보편교저；이IgG항체방면,Tox、CMV급HSV IgG항체양성솔수착년령적증장정현상승추세,단RV IgG항체양성솔각수착년령적증장정하강추세.육령녀성인군적CMV화HSV IgG항체양성솔현저고우남성(x2=83.470화7.026,P＜0.01).결론 하남성육령인군중존재일정비례적TORCH현증감염급교저적RV IgG양성솔,건의육령인군잉전진행TORCH사사.
Objective To investigate the prevalence of toxoplasma gondii (Tox),rubella virus (RV),cytomegalovirus (CMV) and herpes simplex virus (HSV) infections (TORCH infections) among childbearing-age population in Henan province.Methods Enzyme-linked immunosorbent assay (ELISA) was applied to detect plasma TORCH IgM and IgG among 3084 childbearing-age men and women from theFirst Affiliated Hospital of Zhengzhou University during July and September,2011.The positive rates of anti-TORCH antibodies were compared among the various age and gender groups by x2 test.Results The total positive rate of anti-TORCH IgM was 5.5％ (170/3084),in which the positive rate of anti-RV IgM was the highest (2.9％),followed by anti-HSV IgM (1.0％).Within positive rate of anti-TORCH IgG,anti-HSV IgG was the highest (90.4％),followed by anti-CMV IgG (89.7％),RV IgG (48.1％) and Tox IgG (0.7％).The positive rate of anti-TORCH IgM was the lowest in individuals aged ＞ 30-40 year old.With the age increasing,the positive rates of anti-Tox IgG,anti-CMV IgG and anti-HSV IgG increased,but the positive rate of anti-RV IgG decreased.Women had higher positive rates of anti-CMV IgG and antiHSV IgG than men (x2 =83.470 and 7.026,P ＜ 0.O1).Conclusions Current infection of TORCH exists in childbearing-age population of Henan province,and the positive rate of anti-RV IgG is low.It is recommended to screen for TORCH infection in childbearing-age men and women.
