中华临床感染病杂志
中華臨床感染病雜誌
중화림상감염병잡지
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
2014年
2期
183-187
,共5页
手足口病%肠道病毒71%发病机制%治疗
手足口病%腸道病毒71%髮病機製%治療
수족구병%장도병독71%발병궤제%치료
Hand,foot and mouth disease%Enterovirus 71%Pathogenesis%Therapy
重症手足口病病例主要由肠道病毒71型(EV71)感染引起,致死的主要原因是脑干脑炎和神经源性肺水肿.手足口病的治疗需要根据患者所处疾病分期采取不同策略,主要包括针对病原的抗病毒治疗和出现心肺功能受累后的处理.大多数患者随着病情好转后神经系统损害逐渐减轻并痊愈,少数危重病例可能存有后遗症.此文对近年来重症手足口病的发病机制及治疗等相关研究进展作了综述.
重癥手足口病病例主要由腸道病毒71型(EV71)感染引起,緻死的主要原因是腦榦腦炎和神經源性肺水腫.手足口病的治療需要根據患者所處疾病分期採取不同策略,主要包括針對病原的抗病毒治療和齣現心肺功能受纍後的處理.大多數患者隨著病情好轉後神經繫統損害逐漸減輕併痊愈,少數危重病例可能存有後遺癥.此文對近年來重癥手足口病的髮病機製及治療等相關研究進展作瞭綜述.
중증수족구병병례주요유장도병독71형(EV71)감염인기,치사적주요원인시뇌간뇌염화신경원성폐수종.수족구병적치료수요근거환자소처질병분기채취불동책략,주요포괄침대병원적항병독치료화출현심폐공능수루후적처리.대다수환자수착병정호전후신경계통손해축점감경병전유,소수위중병례가능존유후유증.차문대근년래중증수족구병적발병궤제급치료등상관연구진전작료종술.
It has been revealed that most patients with severe hand,foot and mouth diseases are infected with enterovirus 71 (EV71).The death usually occurs with brain stem encephalitis and neurogenic pulmonary edema.Treatment of hand,foot and mouth disease should be stage-based,mainly includes antivirus treatment and management of impaired cardiopulmonary functions.Neurological damage may regress or disappear with disease recovery in most children,but sequelae may also exist in a few critical cases.This paper reviews the research progress on pathogenesis and treatment of severe hand,foot and mouth diseases.
