中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2013年
6期
428-431
,共4页
周韶炜%毛翎%刘锦铭%杨文兰%施瑾%张悦%卞陆琴
週韶煒%毛翎%劉錦銘%楊文蘭%施瑾%張悅%卞陸琴
주소위%모령%류금명%양문란%시근%장열%변륙금
尘肺病%全肺大容量肺灌洗%肺功能%心肺运动试验
塵肺病%全肺大容量肺灌洗%肺功能%心肺運動試驗
진폐병%전폐대용량폐관세%폐공능%심폐운동시험
Pneumoconiosis%Whole lung lavage%Pulmonary function,Cardiopulmonary exercise test
目的 探讨大容量肺灌洗对尘肺患者肺功能和运动能力的影响.方法 选择脱离粉尘作业不超过6个月的尘肺患者41例进行全肺大容量肺灌洗(WLL),对灌洗前和灌洗后1周的临床症状、静态肺功能(PFT)和心肺运动试验(CPET)结果进行比较.结果 灌洗前后临床症状无明显差异.灌洗后1周用力肺活量(FVC)、第1秒用力呼气容积(FEV1.0)和第1秒用力呼气容积占预计值百分比(FEV1.0％)有所上升,但差异无统计学意义(P＞0.05).灌洗后峰值摄氧量从(2140.6±353.2) ml/min上升到(2374.6±362.4) ml/min,峰值摄氧量占预计值百分比从(82.2％±13.7％)上升到(91.0％±14.0％),峰值公斤摄氧量从(30.6±3.5) ml/min上升到(34.2±3.7)ml/min,二氧化碳通气当量最低值从(30.6±3.1)上升至(26.1±2.7),差异有统计学意义(P＜0.05).结论 WLL术能使尘肺患者运动状态时的摄氧能力和通气效率显著提高,从而提高运动能力.
目的 探討大容量肺灌洗對塵肺患者肺功能和運動能力的影響.方法 選擇脫離粉塵作業不超過6箇月的塵肺患者41例進行全肺大容量肺灌洗(WLL),對灌洗前和灌洗後1週的臨床癥狀、靜態肺功能(PFT)和心肺運動試驗(CPET)結果進行比較.結果 灌洗前後臨床癥狀無明顯差異.灌洗後1週用力肺活量(FVC)、第1秒用力呼氣容積(FEV1.0)和第1秒用力呼氣容積佔預計值百分比(FEV1.0％)有所上升,但差異無統計學意義(P＞0.05).灌洗後峰值攝氧量從(2140.6±353.2) ml/min上升到(2374.6±362.4) ml/min,峰值攝氧量佔預計值百分比從(82.2％±13.7％)上升到(91.0％±14.0％),峰值公斤攝氧量從(30.6±3.5) ml/min上升到(34.2±3.7)ml/min,二氧化碳通氣噹量最低值從(30.6±3.1)上升至(26.1±2.7),差異有統計學意義(P＜0.05).結論 WLL術能使塵肺患者運動狀態時的攝氧能力和通氣效率顯著提高,從而提高運動能力.
목적 탐토대용량폐관세대진폐환자폐공능화운동능력적영향.방법 선택탈리분진작업불초과6개월적진폐환자41례진행전폐대용량폐관세(WLL),대관세전화관세후1주적림상증상、정태폐공능(PFT)화심폐운동시험(CPET)결과진행비교.결과 관세전후림상증상무명현차이.관세후1주용력폐활량(FVC)、제1초용력호기용적(FEV1.0)화제1초용력호기용적점예계치백분비(FEV1.0％)유소상승,단차이무통계학의의(P＞0.05).관세후봉치섭양량종(2140.6±353.2) ml/min상승도(2374.6±362.4) ml/min,봉치섭양량점예계치백분비종(82.2％±13.7％)상승도(91.0％±14.0％),봉치공근섭양량종(30.6±3.5) ml/min상승도(34.2±3.7)ml/min,이양화탄통기당량최저치종(30.6±3.1)상승지(26.1±2.7),차이유통계학의의(P＜0.05).결론 WLL술능사진폐환자운동상태시적섭양능력화통기효솔현저제고,종이제고운동능력.
Objective To investigate the effects of whole lung lavage (WLL) on the pulmonary function and exercise capacity in patients with pneumoconiosis.Methods Forty-one patients with pneumoconiosis who quit dust-exposed work not more than 6 months before underwent WLL.Clinical symptom assessment,pulmonary function test,and cardiopulmonary exercise test were performed before and one week after WLL,and the results were compared.Results The patients with pneumoconiosis showed no significant changes in clinical symptoms after WLL.At one week after WLL,the patients with pneumoconiosis showed nonsignificant increases in forced vital capacity,forced expiratory volume in one second (FEV1.0),and percent predicted FEV 1 (P＞0.05); peak oxygen uptake (peak VO2) increased from 2140.6±353.2 ml/min before WLL to 2374.6±362.4ml/min after WLL,percent predicted peak VO2 increased from 82.2±13.7％ before WLL to 91.0±14.0％ after WLL,peak VO2/kg increased from 30.6±3.5 ml/min ·kg before WLL to 34.2±3.7 ml/min ·kg after WLL,and ventilatory equivalent for carbon dioxide decreased from 30.6±3.1 before WLL to 26.1±2.7 after WLL (P＜0.05).Conclusion WLL can remarkably improve the oxygen uptake and ventilatory efficiency in patients with pneumoconiosis during exercise,so it can improve the exercise capacity of these patients.
