CAJ | 학술논문

目的探讨甲苯二异氰酸酯(TDI)对长期接触的作业人员肺功能水平的影响.方法将TDI接触工人且2009至201 1年3年体检资料完整者作为接触组(45人),同时选择该公司的行政人员、后勤人员等TDI非接触者且近3年体检资料完整者作为对照组(47人),比较两组对象的肺功能指标水平.结果 2009年暴露组第1秒用力呼气量(FEV1.0)、第1秒用力呼气量/用力肺活量(FEV10/FVC)以及50％肺活量最大呼气流量(MEF25)水平明显低于对照组,2010年暴露组FEV1.0、FEV1.0/FVC、最大通气量(MVV)及MEF50水平明显低于对照组,2011年暴露组FEV1.0、FEV1.0/FVC、呼气峰流量(PEF)、MEF25及MEF50明显低于对照组,差异均有统计学意义(P＜0.05).结论长期接触TDI对工人的肺功能可造成一定损伤.
목적 탐토갑분이이청산지(TDI)대장기접촉적작업인원폐공능수평적영향.방법 장TDI접촉공인차2009지201 1년3년체검자료완정자작위접촉조(45인),동시선택해공사적행정인원、후근인원등TDI비접촉자차근3년체검자료완정자작위대조조(47인),비교량조대상적폐공능지표수평.결과 2009년폭로조제1초용력호기량(FEV1.0)、제1초용력호기량/용력폐활량(FEV10/FVC)이급50％폐활량최대호기류량(MEF25)수평명현저우대조조,2010년폭로조FEV1.0、FEV1.0/FVC、최대통기량(MVV)급MEF50수평명현저우대조조,2011년폭로조FEV1.0、FEV1.0/FVC、호기봉류량(PEF)、MEF25급MEF50명현저우대조조,차이균유통계학의의(P＜0.05).결론 장기접촉TDI대공인적폐공능가조성일정손상.
Objective To investigate the effect of long-term exposure to toluene diisocyanate (TDI) on the lung function of TDI-exposed workers.Methods A factory was selected for this occupational epidemiological investigation.The workers who were exposed to TDI and had complete physical examination records in recent 3 years were the exposed group (n=45),while the company's administrative staff,logistics staff,and other nonTDI-exposed workers who had complete physical examination records in recent 3 years were the control group (n=47).The two groups were compared in terms of lung function indices.Results Compared with the control group,the 2009 exposure group had significantly lower forced expiratory volume in one second (FEV1.0),FEV1.0/forced vital capacity (FVC),and maximal expiratory flow at 25％ ofFVC (MEF25) (P＜0.05),the 2010 exposure group had significantly lower FEV1.0,FEV1.0/FVC,maximum voluntary ventilation (MVV),and maximal expiratory flow at 50％ ofFVC (MEF50) (P＜0.05),and the 2011 exposure group had significantly lower FEV1.0,FEV1.0/FVC,peak expiratory flow (PEF),MEF25,and MEF50 (P＜0.05).Conclusion Long-term exposure to TDI can lead to certain impairment of lung function in workers,which may be reflected by decreased lung function indices such as vital capacity,FVC,FEV1.0,FEV1.0/FVC,PEF,and MVV.