中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2014年
9期
701-703
,共3页
尘肺%肺纤维化%病理学
塵肺%肺纖維化%病理學
진폐%폐섬유화%병이학
Pneumoconiosi%Pulmonary fibrosis%Pathology
目的 探讨煤工尘肺肺组织进行性大块纤维化(PMF)的病理学特征.方法 对8例煤工尘肺的尸检资料采用HE染色光学显微镜下观察,并结合职业史进行回顾性分析.结果 8例患者年龄47～71岁(平均59.9岁),接尘工龄18～32年(平均25.1年).均并发慢性支气管炎、肺气肿,7例并发肺心病,4例并发肺结核.本组PMF主要分布在肺门及肺上叶,7例为结节融合型,1例为PMF型.PMF周边的胶原纤维组织均呈放射状延伸,并破坏周围组织.结论 煤工尘肺肺组织的PMF的形态以结节融合型为主,呈进行性、破坏性的过程,是晚期煤工尘肺的表现.
目的 探討煤工塵肺肺組織進行性大塊纖維化(PMF)的病理學特徵.方法 對8例煤工塵肺的尸檢資料採用HE染色光學顯微鏡下觀察,併結閤職業史進行迴顧性分析.結果 8例患者年齡47～71歲(平均59.9歲),接塵工齡18～32年(平均25.1年).均併髮慢性支氣管炎、肺氣腫,7例併髮肺心病,4例併髮肺結覈.本組PMF主要分佈在肺門及肺上葉,7例為結節融閤型,1例為PMF型.PMF週邊的膠原纖維組織均呈放射狀延伸,併破壞週圍組織.結論 煤工塵肺肺組織的PMF的形態以結節融閤型為主,呈進行性、破壞性的過程,是晚期煤工塵肺的錶現.
목적 탐토매공진폐폐조직진행성대괴섬유화(PMF)적병이학특정.방법 대8례매공진폐적시검자료채용HE염색광학현미경하관찰,병결합직업사진행회고성분석.결과 8례환자년령47～71세(평균59.9세),접진공령18～32년(평균25.1년).균병발만성지기관염、폐기종,7례병발폐심병,4례병발폐결핵.본조PMF주요분포재폐문급폐상협,7례위결절융합형,1례위PMF형.PMF주변적효원섬유조직균정방사상연신,병파배주위조직.결론 매공진폐폐조직적PMF적형태이결절융합형위주,정진행성、파배성적과정,시만기매공진폐적표현.
Objective To study the pathological features of progressive massive fibrosis (PMF) in the lung tissues of patients with coal workers' pneumoconiosis (CWP).Methods A retrospective analysis was made on the autopsies from 8 patients with CWP,which were observed under a microscope by HE staining,given their occupational history.Results The age of 8 cases ranged 47-71 years (mean,59.9 years),and their dust exposure time was 18-32 years (mean,25.1 years).All the 8 cases were complicated by chronic bronchitis as well as emphysema,7 cases by pulmouary heart disease,and 4 cases by pulmonary tuberculosis.In this group of patients,PMF was mainly distributed in the hilum and the upper lobe of the lung,including 7 cases of nodular fusion type and 1 case of PMF type.The collagen fibers around PMF extended radially and destroyed its surrounding tissue.Conclusion Nodular fusion type is the main form of PMF in the lung tissues of CWP patients.It has a progressive and destructive process,which is the manifestation of advanced CWP.
