中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
10期
903-905
,共3页
孙青%王淑娥%付舒倩%姜迎%徐贵发
孫青%王淑娥%付舒倩%薑迎%徐貴髮
손청%왕숙아%부서천%강영%서귀발
大豆食品%钙,膳食%骨密度
大豆食品%鈣,膳食%骨密度
대두식품%개,선식%골밀도
Soy foods%Calcium,dietary%Bone mineral density
目的 探讨大豆肽钙对大鼠钙表观吸收率及骨密度的影响. 方法 将雄性Wistar 大鼠50只按体质量均衡原则随机分为5 组:低钙对照组、碳酸钙对照组及大豆肽钙低、中、高剂量组,各组大鼠自由进食相应的专配饲料.实验第4周末,进行3 d的钙代谢实验,计算各组的钙表观吸收率;大鼠喂养13周后处死,剥离左、右侧股骨.取右侧股骨测定骨钙含量,左侧股骨测定骨密度.结果 (1)钙代谢实验:碳酸钙对照组钙表观吸收率为69.9％,而中、高剂量大豆肽钙组分别为82.6％和77.4％,差异有统计学意义(F=31.371,P=0.000,0.001);(2)骨密度实验:与低钙对照组比较,大豆肽钙中、高剂量组大鼠体质量(F=3.150.P=0.010,0.002)、股骨质量(F=3.195.P=0.015,0.002)、骨钙含量(F=4.506,P=0.004,0.001)、股骨中点骨密度(F =6.185,P=0.006,0.000)及远心端骨密度(F =6.081,P=0.027,0.000)均增加明显,与碳酸钙对照组比较,除体质量指标(F=3.150,P=0.212)外,大豆肽钙高剂量组也呈现相同的结果(P值分别为0.046,0.024,0.013,0.001). 结论 大豆肽钙可促进钙的吸收,增加大鼠骨密度.
目的 探討大豆肽鈣對大鼠鈣錶觀吸收率及骨密度的影響. 方法 將雄性Wistar 大鼠50隻按體質量均衡原則隨機分為5 組:低鈣對照組、碳痠鈣對照組及大豆肽鈣低、中、高劑量組,各組大鼠自由進食相應的專配飼料.實驗第4週末,進行3 d的鈣代謝實驗,計算各組的鈣錶觀吸收率;大鼠餵養13週後處死,剝離左、右側股骨.取右側股骨測定骨鈣含量,左側股骨測定骨密度.結果 (1)鈣代謝實驗:碳痠鈣對照組鈣錶觀吸收率為69.9％,而中、高劑量大豆肽鈣組分彆為82.6％和77.4％,差異有統計學意義(F=31.371,P=0.000,0.001);(2)骨密度實驗:與低鈣對照組比較,大豆肽鈣中、高劑量組大鼠體質量(F=3.150.P=0.010,0.002)、股骨質量(F=3.195.P=0.015,0.002)、骨鈣含量(F=4.506,P=0.004,0.001)、股骨中點骨密度(F =6.185,P=0.006,0.000)及遠心耑骨密度(F =6.081,P=0.027,0.000)均增加明顯,與碳痠鈣對照組比較,除體質量指標(F=3.150,P=0.212)外,大豆肽鈣高劑量組也呈現相同的結果(P值分彆為0.046,0.024,0.013,0.001). 結論 大豆肽鈣可促進鈣的吸收,增加大鼠骨密度.
목적 탐토대두태개대대서개표관흡수솔급골밀도적영향. 방법 장웅성Wistar 대서50지안체질량균형원칙수궤분위5 조:저개대조조、탄산개대조조급대두태개저、중、고제량조,각조대서자유진식상응적전배사료.실험제4주말,진행3 d적개대사실험,계산각조적개표관흡수솔;대서위양13주후처사,박리좌、우측고골.취우측고골측정골개함량,좌측고골측정골밀도.결과 (1)개대사실험:탄산개대조조개표관흡수솔위69.9％,이중、고제량대두태개조분별위82.6％화77.4％,차이유통계학의의(F=31.371,P=0.000,0.001);(2)골밀도실험:여저개대조조비교,대두태개중、고제량조대서체질량(F=3.150.P=0.010,0.002)、고골질량(F=3.195.P=0.015,0.002)、골개함량(F=4.506,P=0.004,0.001)、고골중점골밀도(F =6.185,P=0.006,0.000)급원심단골밀도(F =6.081,P=0.027,0.000)균증가명현,여탄산개대조조비교,제체질량지표(F=3.150,P=0.212)외,대두태개고제량조야정현상동적결과(P치분별위0.046,0.024,0.013,0.001). 결론 대두태개가촉진개적흡수,증가대서골밀도.
Objective To investigate the effects of soybean peptide calcium on apparent calcium absorption rate and bone mineral density of rats.Methods Totally 50 male Wistar rats were divided into 5 groups at comparable body weight:the low calcium control group,calcium carbonate control group and 3 groups with low,medium and high dose of soybean peptide calcium(SPC).Rats of each group were fed with designed forage.At the end of the fourth week of the feeding.calcium metabolic experiment was performed for 3 days and the apparent calcium absorption rate was calculated.Three months later,the left and right femurs of the rats were stripped to assay the bone calcium and bone density.Results Apparent calcium absorption rate of the calcium carbonate control group was 69.9 ％,which was lower than medium(82.6 ％) and high doses(77.4％) of soybean peptide calcium groups(F =31.371,P=0.000,0.001).Compared with the low calcium control group,rats with medium and high doses of SPC had obviously increased levels of weights(F =3.150,P =0.010,0.002),bone mass(F =3.195,P =0.015,0.002),calcium content (F=4.506,P =0.004,0.001)and bone mineral density of midpoint (F=6.185,P =0.006,0.000) and far end of femur (F =6.081,P=0.027,0.000).Despite of the weight index (P＞0.05),the high dose of soybean peptide calcium group also had the same results as the calcium carbonate control group (P=0.046,0.024,0.013,0.001).Conclusions Soybean peptide calcium can promote the apparent calcium absorption rate and increase the bone mineral density.
